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Research Article Open access CC BY 4.0

Study of the Relation between Aging and Pesticides: A Review

Renata Cristina-Pereira, Anna Luiza de Araújo Ribeiro, Anna Cláudia Ferreira Nunes, Luca Casale Guereschi, Maria Amália Garcia da Silveira Araújo, Maria Tereza Gonçalves-Mendes, Kaynara Trevisan, Heberson Teixeira da Silva, Tales Alexandre Aversi-Ferreira

International Neuropsychiatric Disease Journal · pp. 26–46 · Published 13 May 2024

10.9734/indj/2024/v21i4440

Abstract

Aims: The main aim of this study was to use specific data from the literature on ageing, correlating this with the pesticide contamination, in order to understand the relationship with an increasingly ageing population. Study Design: A systematic review was performed. Place and Duration of Study: Laboratory of Biomathematics of the Federal University of Alfenas, Minas Gerais State, Brazil, between April 2023 and August 2023. Methodology: A systematic search of articles was performed using the CAPES Periodic platform, a searcher from the Education Ministry of Brazil that contains Web of Science, Scopus, MedLine, from August 2020 to May 2023. For this review, the subject’s “aging theory”; “neuroscience and pathologies to aging”; “aging and aging-associated changes”; “pesticides and pesticide toxicity”; “pesticide toxicity and neurotoxicity”; “longevity and healthy aging”; “aging human and pesticides” were searched together using the type of material “articles” in English language. Some articles about “population growth”; “world population”; “population-aging” were used for epistemological composition of this work content subjects. Results: From the 19.720 articles after the exclusion and the inclusion criteria made with the subjects most pertinent to the objectives of this work; 19.570 articles were excluded, remaining 150 ones, of which 116 were qualitative in scope and 34 quantitative. Conclusion: The complex relationship between the pesticide contamination and the condition of the exposed individual may be associated with premature ageing and a greater susceptibility to debilitating age-related diseases. Although technology is increasingly improved in its innovations, health and environmental regulations have not been able to rid the production processes of their potential to pollute the environment and cause health problems for those exposed to them.

Aging theory precocious aging pesticide free radicals oxidative stress epigenome

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