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Research Article Open access CC BY 4.0

Isolation and Characterization of Bergapten from the Root Bark of Ficus exasperata (Vahl)

O. E. Famobuwa, A. A. Agbowuro, E. A. Adekunbi, M. A. Akinwale

International Journal of Biochemistry Research & Review · pp. 1–5 · Published 25 Mar 2019

10.9734/ijbcrr/2019/v25i330075

Abstract

Despite the wide ethnomedicinal applications of Ficus exasperata, little is known about the active principles responsible for the observed biological effects, thus limiting opportunities for further therapeutic applications. The bioassay guided chemical investigation of F. exasperata root bark resulted in the isolation of a furocoumarin (D-1) shown to be partly responsible for the acclaimed anti-diabetic effect of the plant.

Ficus exasperata root bark bergapten furocoumarin anti-diabetic effect.

Cited by 2

Bergapten: A review of its pharmacology, pharmacokinetics, and toxicity

Youdan Liang, Long Xie, Kai Liu · Phytotherapy Research · 2021

Coumarins from the peel of citrus grown in Colombia: composition, elicitation and antifungal activity

Cesar Ramírez-Pelayo, Janio Martínez-Quiñones, Jesús Gil · Heliyon · 2019

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