Possible Steroid-responsive Encephalopathy Associated with Autoimmune Thyroiditis (SREAT) in a Patient with Impaired Consciousness
Shaily Shah, Bhaumil Shah, Pramod Jha
Asian Journal of Research and Reports in Neurology · pp. 23–26 · Published 6 Apr 2023
Abstract
Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT), also known as Hashimoto’s encephalopathy (HE) is a rare neurological disorder associated with thyroid autoimmunity. Clinical manifestations include seizures, altered consciousness, transient aphasia, tremors, myoclonus, cognitive impairment, and psychiatric manifestations. Here, we report a case of a 55-year-old female presenting with altered sensorium for 4 days. The patient was a known case of Hypothyroidism, Hypertension and Diabetes. Serologic studies demonstrated elevated levels of anti-thyroid peroxidase (anti-TPO) antibodies. The patient showed a remarkable response to steroid therapy. Hence, the diagnosis of SREAT should be suspected in cases of encephalopathy without an obvious cause, as a good response can be obtained withsteroid therapy; early diagnosis and treatment are very beneficial for such patients.
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