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Research Article Open access CC BY 4.0

Role of Kisspeptin in Puberty in Humans

Ravi Kant, Mahendra Kumar Meena

Journal of Advances in Medicine and Medical Research · pp. 92–97 · Published 6 Aug 2020

10.9734/jammr/2020/v32i1230545

Abstract

Kisspeptin or GPR-54 is a product of KISS 1 gene regulating the production of gonadotropin releasing hormone (GnRH), luteinizing (LH) as well follicle stimulating hormone (FSH). Both LH and FSH are important hormones for reproduction in animals as well in humans. The recognition of Kisspeptin has a landmark bearing in reproductive biology. Few recent pilot studies have convincingly proven it to be a promising molecule in treating infertile couples especially those having hypogonadotropic hypogonadism not responding to conventional treatment.

Kisspeptin GPR-54 gonadotropin releasing hormone luteinizing hormone follicle stimulating hormone hypogonadotropic hypogonadism.

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