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Research Article Open access CC BY 4.0

Role of Cytokines and Vaccines in Break through COVID 19 Infections

Richard Owusu Nyarko, Purabi Saha, Roshan Kumar, Ivan Kahwa, Edward Amoah Boateng, Paul Owusu Boateng, Asum Christian, Asare Bertram

Journal of Pharmaceutical Research International · pp. 2544–2549 · Published 26 Dec 2021

10.9734/jpri/2021/v33i60B34912

Abstract

Background: Despite efforts to develop a COVID-19 vaccine, it has failed to provide long-term immunity and protection against COVID-19 and the newly worrying SARS-CoV-2 coronavirus strains. Understanding cytokines, which are key in generating unique immune responses from pathogenic organisms, is important for creating vaccines. Objective: In order to better understand cytokines and how the current COVID-19 vaccinations can assist reactivate latent cytokines, the scientific community and the general public must be educated. Materials and Methods: Medical and scientific indexing sources like PubMed and Google Scholar were used to search for relevant medical and scientific publications. Results: After vaccination, cytokines in the immune system can be activated, which can help signal chemicals that can increase the immune system's ability to fight against new and break-through COVID 19 infections. Conclusion:  It has been discovered that both the Pfizer-BioNTech and the Moderna vaccines are safe and effective in preventing break through COVID-19 infections, regardless of whether the patient experiences symptoms or not. It is an adenovirus, not an mRNA, that Johnson & Johnson's vaccine is made of.

Cytokines COVID-19 immunity Pfizer-BioNTech Moderna Johnson & Johnson

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