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Research Article Open access CC BY 4.0

Protective effect of Boysenberry Juice on Ferric Nitrilotriacetate-induced Renal Injury in Mice

Takashi Hashimoto, Maki Kiyota, Kazuki Kanazawa

European Journal of Medicinal Plants · pp. 76–81 · Published 1 Jul 2021

10.9734/ejmp/2021/v32i430386

Abstract

Boysenberry (Rubus loganbaccus × baileyanus Britt.) is one of the popular berries in Western countries. In the present study, the effect of the boysenberry juice on ferric nitrilotriacetate (Fe-NTA)-induced renal injury was investigated. ICR mice (7 weeks old, male) were ad libitum administered boysenberry juice for 1 week, and were intraperitoneally injected Fe-NTA (5 mg Fe/kg body weight) as an oxidant to renal. The consumption of boysenberry juice suppressed the Fe-NTA-increased thiobarbituric acid reactive substances (TBARS) in kidney and blood urea nitrogen (BUN). These results indicate that the consumption of boysenberry juice reduces the risk of oxidative stress.

Boysenberry ferric nitrilotriacetate renal injury antioxidative activity anthocyanins mice

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