Skip to content
T

Takashi Hashimoto

Publications (4)

Dietary Isosaponarin is Intestinally Metabolized to Isovitexin, Most of Which are Excreted in Feces without Being Absorbed

Takashi Hashimoto, Jiansheng Long & Kazuki Kanazawa · Asian Journal of Food Research and Nutrition · 2023

Objective: The metabolism of isosaponarin was investigated using a Caco-2 intestinal epithelial model and animal experiment. Background: Isosaponarin is a flavonoid in wasabi (Wasabia japonica) leaves and has unique structure, in which two glucose molecules bind to apigenin throu...

Open access Research Article

Protective effect of Boysenberry Juice on Ferric Nitrilotriacetate-induced Renal Injury in Mice

Takashi Hashimoto, Maki Kiyota & Kazuki Kanazawa · European Journal of Medicinal Plants · 2021

Boysenberry (Rubus loganbaccus × baileyanus Britt.) is one of the popular berries in Western countries. In the present study, the effect of the boysenberry juice on ferric nitrilotriacetate (Fe-NTA)-induced renal injury was investigated. ICR mice (7 weeks old, male) were ad libit...

Open access Research Article 10.9734/ejmp/2021/v32i430386

6-Methylsulfinylhexyl Isothiocyanate Inhibits Cell Cycle Progression in Quiescent Jb6 Cells Stimulated with Epidermal Growth Factor

Takashi Hashimoto, Maki Kobayashi & Kazuki Kanazawa · Annual Research & Review in Biology · 2021

Objective: The effects of 6-MSITC on cell cycle progression were investigated in quiescent mouse epidermal JB6 cells. Background: 6-Methylsulfinylhexyl isothiocyanate (6-MSITC) derived from wasabi (Wasabia japonica) has been reported to prevent tumor development in vivo. Material...

Open access Research Article 10.9734/arrb/2021/v36i630386

Artepillin C Inhibits Cell Proliferation by Cell Cycle Arrest at G0/G1 Phase Accompanied by Up-Regulation of p27Kip1 in Human Hepatoma HepG2 Cells

Takashi Hashimoto, Weitao Shang & Kazuki Kanazawa · Journal of Complementary and Alternative Medical Research · 2021

Artepillin C, 3, 5-diprenyl-4-hydroxycinnamic acid, is one of the bioactive constituents in Brazilian propolis. In the present study, the anticarcinogenic activity of this compound was investigated in human hepatoma HepG2 cells. Artepillin C inhibited the cell proliferation in a...

Open access Research Article 10.9734/jocamr/2021/v14i130236