Plant Bioactives and Biotechnological Approaches to Enhance Their Production and Bioactivity
G. Janarny, H. A. C. O. Hettiarachchi, N. N. G. Chiranthika, K. D. P. P. Gunathilake
Asian Journal of Biotechnology and Genetic Engineering · pp. 30–51 · Published 20 Feb 2022
Abstract
Plants considered as an excellent source for discovering new compounds with medicinal significance in drugs/ functional foods/ nutraceutical formulations. Bioactive compounds of found in plants are those secondary metabolites exhibiting health benefit in human. It is obvious that studies related to plant bioactives engaging to develop in many aspects involving researchers from different scientific disciplines. In the explore for alternatives for producing and enhancing the desirable bioactives from plants, biotechnological approaches such as fermentation, plant tissue culture, metabolic engineering, genetic transformation, plant cell elicitation, microencapsulation (as delivery mode) are found to have potential in industrial production of bioactive plant metabolites. The present review discusses the different categories of plant bioactives along with an overview of their medicinal applications as antioxidants, anti-inflammatory agents, anti-diabetic and anti-cancer agents. The current trend on applications of recent biotechnological tools in the production of plant bioactives has also been discussed.
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