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Research Article Open access CC BY 4.0

Pontederia crassipes Biosynthesised Silver Nanoparticles (AgNPs), Characterisation and Activity against Multidrug-Resistant Microbes

T. C Semu, J Williams, J. Cheng, I Mutingwende, J Chifamba

Journal of Advances in Medical and Pharmaceutical Sciences · pp. 1–16 · Published 26 Apr 2024

10.9734/jamps/2024/v26i6690

Abstract

Introduction: Pontederia crassipes (water hyacinth) has been singled out as one of the major causes of enormous economic and ecological losses to tropical water systems and habitats. Almost impossible to eradicate, the ominous species is characterized by rapid multiplication, giving rapid and extensive spread that can choke entire rivers and water bodies. However, vast, diverse bioactive secondary metabolites are found in P crassipes which exhibit an expansive assortment of antibacterial properties used in traditional medicine. The rapid emergence of Multi Drug Resistant (MDR) pathogens to common drugs is a pandemic of global proportions. Global health institutions are calling for a coordinated, global action plan to develop new biomaterials to combat the rising threat by MDR strains and improve treatment outcomes and save lives. This study proposes consumption of the water hyacinth lily species through a novel, material biosynthesis approach not only to manage the aquatic infestation but to develop advanced multifunctional, anti-microbial Silver nanoparticles through bio-reduction and capping of Silver salts targeted at MDR microbes. Methodology: After screening for active phytoconstituents of P.crassipes. The Biosynthesis of Novel AgNPs mediated by phenolic, antibacterial lyophilized hydro-ethanolic extracts from P crassipes as both bioreduction and capping agents was investigated. The resultant AgNPs characteristics, toxicological profiles and the antibacterial effects on 10 common microbes including MDR bacterial strains were evaluated. Observations and Results: TEM revealed that cubic and spherical nanometric AgNPs structures were successfully synthesized with particle size range from 10-60nm. With an average zone of inhibition of 29mm and an MIC of 6.25 µg/ml .The nanoparticles were efficacious against selected MDR strains and common infectious bacterial strains tested. In-vivo acute oral toxicity evaluations confirmed the safety of P crassipes. Conclusion: Biogenic P.crassipes mediated AgNPs are feasible, safe and efficacious and have immense potential for optimization into efficient broad spectrum MDR antibacterial agents.

Pontederia crassipes water hyacinth antibacterial resistance biosynthesis silver nanoparticles polyphenols

References (34)

  1. 1 Origins and Evolution of Antibiotic Resistance [DOI]
  2. 2 Green synthesis of metal nanoparticles using plants [DOI]
  3. 3 Antibiotic resistance in the environment [DOI]
  4. 4 Methicillin-Resistant Staphylococcus aureus: Molecular Characterization, Evolution, and Epidemiology [DOI]
  5. 5 Prevalence of Antibiotic Resistance in Helicobacter pylori: A Systematic Review and Meta-analysis in World Health Organization Regions [DOI]
  6. 6 Environmental factors influencing the development and spread of antibiotic resistance [DOI]
  7. 7 A Review on Antibiotic Resistance: Alarm Bells are Ringing [DOI]
  8. 8 The 3Rs and Humane Experimental Technique: Implementing Change [DOI]
  9. 9 Antibiotic Resistance: One Health One World Outlook [DOI]
  10. 10 Biological agents for synthesis of nanoparticles and their applications [DOI]
  11. 11 Green Synthesis of Selenium Nanoparticle Using Leaves Extract of Withania somnifera and Its Biological Applications and Photocatalytic Activities [DOI]
  12. 12 Distribution of antibiotic resistance genes in the environment [DOI]
  13. 13 Macrolide and Nonmacrolide Resistance with Mass Azithromycin Distribution [DOI]
  14. 14 Environmental hotspots for antibiotic resistance genes [DOI]
  15. 15 Invasive Water Hyacinth: Ecology, Impacts and Prospects for the Rural Economy [DOI]
  16. 16 Defining body-weight reduction as a humane endpoint: a critical appraisal [DOI]
  17. 17 Eichhornia crassipes (Mart.) Solms: A Comprehensive Review of Its Chemical Composition, Traditional Use, and Value-Added Products [DOI]
  18. 18 Green fabrication, characterization of silver nanoparticles using aqueous leaf extract of Ocimum americanum (Hoary Basil) and investigation of its in vitro antibacterial, antioxidant, anticancer and photocatalytic reduction [DOI]
  19. 19 Water hyacinth control in Lake Victoria: Transforming an ecological catastrophe into economic, social, and environmental benefits [DOI]
  20. 20 Green Biogenic of Silver Nanoparticles Using Polyphenolic Extract of Olive Leaf Wastes with Focus on Their Anticancer and Antimicrobial Activities [DOI]
  21. 21 Antibiotic Resistance and Its Impact on Disease Management [DOI]
  22. 22 A Review on Alternative Methods to Experimental Animals in Biological Testing: Recent Advancement and Current Strategies [DOI]
  23. 23 Surface Plasmons and Vibrations of Self-Assembled Silver Nanocolumns [DOI]
  24. 24 Methicillin-Resistant Staphylococcus aureus [DOI]
  25. 25 The global and regional prevalence, burden, and risk factors for methicillin-resistant Staphylococcus aureus colonization in HIV-infected people: A systematic review and meta-analysis [DOI]
  26. 26 Microbial Susceptibility and Plasmid Profiles of Methicillin-Resistant Staphylococcus aureus and Methicillin-Susceptible S. aureus [DOI]
  27. 27 Comparative Biochemistry [DOI]
  28. 28 Methicillin-Sensitive and Methicillin-Resistant Staphylococcus aureus: Preventing Surgical Site Infections Following Plastic Surgery [DOI]
  29. 29 Phenalene metabolites from eichhornia crassipes [DOI]
  30. 30 A bioactive benzoindenone from Eichhornia crassipes solms [DOI]
  31. 31 Isolation and chemical evaluation of protein from water hyacinth [DOI]
  32. 32 A probabilistic model of competitive multi-ecological interactions for analyzing the impact of noise within sight of aquatic hyacinth [DOI]
  33. 33 Dynamics of Water Hyacinth in a Fishery System with Delay Effect [DOI]
  34. 34 Methicillin-Sensitive and Methicillin-Resistant Staphylococcus aureus: Preventing Surgical Site Infections Following Plastic Surgery [DOI]

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