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J Chifamba

Publications (12)

Validation of Biosafety and Activity of Albizia antunesiana Lyophilised Leaf Extracts

J Chifamba, O T CHIKORE & G MANYUCHI · Journal of Complementary and Alternative Medical Research · 2025

Albizia antunesiana, from the Fabaceae family is a widespread plant species prevalent in tropical and subtropical regions of Africa. The plant is extensively utilized in traditional medicine for various ailments, particularly in the management of acute and chronic wounds. The use...

Open access Research Article 10.9734/jocamr/2025/v26i7680

Antifertility Activity of Crude Extracts of Pouzolzia mixta in Female Rats

J Chifamba, A MUTAMBA & R MUTUNGA · Journal of Complementary and Alternative Medical Research · 2025

Pouzolzia Mixta (hypoleuca), is a small multi- stemmed shrub tree from the Urticaceae family found throughout Southern Africa. The dried shrub’s root powder has been the traditional contraception for Zimbabwean women for centuries. Traditionally believed to possess postcoital ant...

Open access Research Article 10.9734/jocamr/2025/v26i7676

Elephantorrhiza elephantina Pharmacological Activity and Bio Safety in Pancreatic Insufficiency End Points

J Chifamba, M CHAKANYUKA, I G NDARIMANI & S. Zengeni · Journal of Complementary and Alternative Medical Research · 2025

Elephantorrhiza elephantina been traditionally used for various medicinal purposes including management of gastrointestinal disorders and inflammatory conditions. Despite its extensive use in traditional medicine, E. elephantina remains largely underutilized due to the limited sc...

Open access Research Article 10.9734/jocamr/2025/v26i7677

Hybrid Sunscreen for Albinistic Skin Types Augmented by Terminalia Sericea Mediated Silver Doped Zinc Oxide Nanoparticles, Efficacy and Safety Investigation

J Chifamba & C Chifamba · Biotechnology Journal International · 2024

Albinism is a congenital hypopigmentation disorder characterized by errors in melanisation leading to the partial or complete absence of melanin, the skin’s primary defense against actinic damage. Actinic damage in albinism summarizes all solar induced consequences from freckles...

Open access Research Article 10.9734/bji/2024/v28i5744

Lyophilised Aloe excelsa Fractions, Photo-protection and Actinic Damage Retardation Claims Substantiation

J Chifamba, A J Addae, S Zengeni, M Pomerai & N Kurebgaseka · Journal of Complementary and Alternative Medical Research · 2024

Introduction: Ultraviolet radiation is potentially harmful to plants’ physiological structures and their photosynthetic apparatus through induction of photo-oxidative damage and photosynthetic inhibition. Aloe excelsa a resilient (sub) tropical plant has evolved various photo-pro...

Open access Research Article 10.9734/jocamr/2024/v25i5536

Skin ‘Bleaching’ Practices and Associated Adverse Health Effects in Zimbabwe: A Canonical Correlational Study of Harare

J Chifamba & T Murairwa · Journal of Pharmaceutical Research International · 2024

The study aimed to identify the ingredients, processes and practitioners involved in the skin lightening practices in Zimbabwe and to identify the associated, adverse health effects as well as to establish the user demographics. A technical field survey was carried out in Harare,...

Open access Research Article 10.9734/jpri/2024/v36i67522

From Zimbabwean Indigenous Knowledge: Scientific Substantiation of the Aphrodisiac Efficacy and Safety of Pittosporum viridiflorum in Male Rat Models

J Chifamba & S Zengeni · International Journal of Biochemistry Research & Review · 2024

Introduction: Pittosporum viridiflorum, the multi habitat thriving plant species is widely believed to have been the source of sexual prowess for the polygamous kings and elites of the mighty medieval empire known as ‘Great Zimbabwe’. Despite the lack of systematic scientific val...

Open access Research Article 10.9734/ijbcrr/2024/v33i5873

Cannabis sativa-Mediated Synthesis of Copper-Doped Zinc Oxide Nanoparticles (Cu2O-ZnONPs), Characterisation and Biomedical Activity Assessment

S Zengeni & J Chifamba · Journal of Materials Science Research and Reviews · 2024

The escalating emergence of antibacterial resistance to most organic drugs by common pathogenic microbes necessitates the search for alternatives. Inorganic metal oxide nanoparticles have displayed in many studies their suitability as substitute treatments for organic antibiotic-...

Open access Research Article 10.9734/jmsrr/2024/v7i4355

Eco-friendly Biosynthesis of Silver Nanoparticles Using Elephantorrhiza elephantina: Characterization and Antimicrobial Activity against Mycobacterium tuberculosis Surrogate Models

W E Chipato & J Chifamba · International Journal of Biochemistry Research & Review · 2024

The emergence of multidrug-resistant (MDR) and extensively-drug resistant (XDR) Mycobacterium tuberculosis (MTB) strains have scampered efforts to arrest the tuberculosis (TB) pandemic due to treatment failures based on current drugs. The need for novel therapeutics has never bee...

Open access Research Article 10.9734/ijbcrr/2024/v33i6912

Biofabricated Zinc Oxide Nanoparticles (ZnONPs) using Annona stenophylla: Their Structural and Activity Characterization

L N Gwaze, W E Chipato & J Chifamba · Journal of Materials Science Research and Reviews · 2024

Biosynthesis of functional nanomaterials from metallic salts using polyphenolic components of plant extracts provides an eco-friendly, easily scalable one pot fabrication of novel biotherapeutics. Among the nanomaterials that can be obtained through green synthesis, Zinc Oxide na...

Open access Research Article 10.9734/jmsrr/2024/v7i4361

Bioactivity and Safety of Lyophilised Carrisa edulis

L N Gwaze, W E Chipato, S Zengeni & J Chifamba · Journal of Materials Science Research and Reviews · 2025

Carissa edulis (C. edulis), from the Apocynaceae family is a widespread plant species prevalent in tropical and subtropical regions of Africa. The plant is extensively utilized in traditional medicine for various ailments, particularly diabetes mellitus (DM), a chronic, non-commu...

Open access Research Article 10.9734/jmsrr/2025/v8i1382

Pontederia crassipes Biosynthesised Silver Nanoparticles (AgNPs), Characterisation and Activity against Multidrug-Resistant Microbes

T. C Semu, J Williams, J. Cheng, I Mutingwende & J Chifamba · Journal of Advances in Medical and Pharmaceutical Sciences · 2024

Introduction: Pontederia crassipes (water hyacinth) has been singled out as one of the major causes of enormous economic and ecological losses to tropical water systems and habitats. Almost impossible to eradicate, the ominous species is characterized by rapid multiplication, giv...

Open access Research Article 10.9734/jamps/2024/v26i6690