Skip to content
Research Article Open access CC BY 4.0

Pharmacognostic Evaluation of the Leaves of Thurnbegia laevis Nees (Acanthaceae)

Romanus A. Umoh, Imoh I. Johnny, Nsima A. Andy, Emmanuel R. Idio, Goodnews E. Charles, Anwanabasi E. Udoh, TiyoAbasi A. Udom, Daniel A. Owineng

Asian Journal of Biochemistry, Genetics and Molecular Biology · pp. 91–103 · Published 4 Nov 2023

10.9734/ajbgmb/2023/v15i3342

Abstract

Thurnbegia laevis Nees. belong to the Acanthaceae family. It is used in folklore medicine for the management of diabetes, piles, joint pains as well as skin related problems. This study aims to evaluate the leaves of the plant by employing the quality control parameters. The leaves of T. laevis were collected, identified, air-dried, pulverized and stored in glass bottles. Standard procedures were used to carry out microscopy on the fresh leaves, micromeritics, chemomicroscopy, fluorescence analysis, soluble-extractive values, moisture contents and ash values using powdered samples of the leaf. Methanol extract of the leaf was used to conduct GC-MS analysis. The result showed that the leaf was amphistomatic with diacytic stomata on both surfaces. The micromeritic studies showed that the leaf had an angle of repose of 37.47ᵒ, Carr’s Index of 23.01% and Hausner’s ratio of 1.3. Water-soluble, ethanol-soluble and methanol-soluble extractive values were 21%w/w, 10%w/w and 11%w/w, respectively. Fluorescence analysis of the leaf showed different colours indicating the presence of different phytochemicals. The moisture content, total ash, acid-insoluble and water-soluble ash values were 5.31%w/w, 15.18%w/w, 2.7%w/w and 5.6%w/w, respectively. Chemomicroscopy of the leaf powder showed the presence of mucilage, lignin, starch, cellulose and protein while, oil and calcium oxalate crystals were absent. The GC-MS analysis showed the presence of thirty-five (35) phytochemicals with compounds like n-Hexadecanoic acid, 9,12,15-Octadecatrienoic acid, Vitamin E, Stigmasterol, Supraene and, Benzoic acid. These compounds have antioxidant, anticonvulsant, antiserum, antifungal, hypoglycaemic, antimicrobial, anti-inflammatory and larvicidal activities. The results stated could be used to establish standards for the authentication of the fresh and powdered drug leaf products of Thunbergia laevis.

GC-MS micromeritics micromorphological pharmacognostic phytochemicals Thunbergia laevis

References (15)

  1. 1 Aulton's pharmaceutics: the design and manufacture of medicines
  2. 2 Aulton's Pharmaceutics : The Design and Manufacture of Medicines
  3. 3 Effect of Feronia limonia on mosquito larvae [DOI]
  4. 4 Anticonvulsant effect of phytol in a pilocarpine model in mice [DOI]
  5. 5 Pharmacognostic evaluation of Cayratia trifolia (Linn.) leaf [DOI]
  6. 6 In-silico Absorption, Distribution, Metabolism, Elimination and Toxicity profile of 9,12,15-Octadecatrienoic acid (ODA) from Moringa oleifera [DOI]
  7. 7 Holm Oak (Quercus ilex subsp. ballota (Desf.) Samp.) Bark Aqueous Ammonia Extract for the Control of Invasive Forest Pathogens [DOI]
  8. 8 CHEMICAL COMPOUNDS INVESTIGATION OF LUCAS ASPERA LEAVES - A POTENTIAL FOLKLORE MEDICINAL PLANT
  9. 9 Formulation development of intermediate release Nimesulide tablets by CCRD for IVIVC studies.
  10. 10 Compositions of Thunbergia grandiflora Leaf and Root Essential Oils [DOI]
  11. 11 Pharmacognostic Characterization of Cola millenii K. Schum. (Malvaceae) [DOI]
  12. 12 Monograph on Glycerin and Its Uses.
  13. 13 Evidence-Based Complementary and Alternative Medicine [DOI]
  14. 14 Pakistan Journal of Pharmaceutical Sciences [DOI]
  15. 15 Journal of Drug Delivery and Therapeutics [DOI]

Cited by 0

No indexed citations yet.

Related research

Article metrics

Real usage data collected on this platform.

78

Page views

0

PDF downloads

29

Outbound clicks

0

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.