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Research Article Open access CC BY 4.0

Nanobiotechnology and its Application in Vaccine Delivery

Reem Farsi

Journal of Pharmaceutical Research International · pp. 39–55 · Published 8 Feb 2022

10.9734/jpri/2022/v34i8A35476

Abstract

The term " Nanobiotechnology " refers to the use of nanotechnology in biological fields. Nanotechnology is a multidisciplinary area that is currently recruiting approaches, technologies, and capabilities from traditional and advanced engineering, physics, chemistry, and biology. Vaccination has made a huge difference in human health. Despite advances in this area, there is no effective vaccine for a large number of diseases, and some of the available ones do not offer long-term immunity. Numerous studies have been conducted recently to determine the feasibility of using nanostructures as an effective method for vaccine delivery, and the initial findings have been encouraging. So, in the present review, we will address which types of nanoparticles are appropriate for vaccine delivery and reveal and discuss the significance of virus-like particles (VLPs), liposomes, polymeric-based nanoparticles Polyanhydride-based nanoparticles for vaccine delivery. It is crucial to understand their size, shape, charge, porosity, and hydrophobic properties. In conclusion, nanotechnology will help to have a brief understanding of nanotechnology in the delivery of vaccines.  So, it could also motivate new strategies for human disease prevention or treatment.

Nanobiotechnology Nanoparticle (NP) Vaccine delivery Virus-like particle Polyanhydride-based nanoparticles liposomes

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