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Research Article Open access CC BY 4.0

Mucormycosis and It’s Prevalence in the Patients of COVID-19

Arya Singh, Dhruba Hari Chandi

Journal of Pharmaceutical Research International · pp. 3246–3252 · Published 27 Dec 2021

10.9734/jpri/2021/v33i60B35000

Abstract

The world today is going through a series of uncalled events, that has hindered the balance of livelihood in the current population. This is due to the emergence of the COVID-19 but along with that, the COVID-19 has accompanied several other rare and extremely fatal fungal infections under its shadows, such as the Mucormycosis. Mucormycosis is caused particularly in the immunocompromised hosts by the saprophytic fungi of Mucorales species. This infection leads to several clinical conditions, under the influence of the COVID-19 Associated Mucormycosis, commonly being the conditions such as the rhino-cerebral disease. This condition occurs mainly in the patients with diabetes mellitus. Several other respiratory, gastrointestinal and cutaneous contaminations also occur during this condition. COVID-9 accompanied with diabetes mellitus can be extremely life threatening. Now, there are several predisposing factor to the Mucormycosis which could accompany the severity of the conditions such as the Ketoacidosis in the patients with diabetes mellitus, patients on the immunosuppressive therapies, previous pulmonary infections and other nosocomial contaminations. There are no specific biomarkers available to diagnose Mucormycosis; Histopathological examination of the biopsied tissue and imaging of the involved area are most important in diagnosis. Mucormycosis being an angioinvasive fungus, usually is present in the surroundings with wet surfaces and dead and decaying vegetable matter. The term black fungus is used as in for the dematiaceous fungi, which are an entirely different group. Since the COVID-19 pandemic is on it’s massive widespread in the country, the new variant being more infectious, people are more tend to some other complications of the COVID-19 contamination such as that of the secondary fungal infections causing high mortality rates.

COVID-19 Mucormycosis fungal infections black fungus histopathology biomarkers clinicopathological findings diabetes mellitus rhino-cerebral disease

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