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Research Article Open access CC BY 4.0

Metabolic Ketoacidosis in a Gravida Diagnosed with COVID-19: A Case Report

Sparsh Madaan, Dhruv Talwar, Sunil Kumar, Arpita Jaiswal, Neema Acharya, Sourya Acharya, Dhruva Halani

Journal of Pharmaceutical Research International · pp. 328–333 · Published 1 Oct 2021

10.9734/jpri/2021/v33i45A32750

Abstract

We present a case of term pregnancy which presented with chief complaint of Breathlessness, chest pain as well as a one day history of vomiting. She tested positive for COVID19 through reverse transcriptase polymerase chain reaction of nasopharyngeal swab and the symptoms were attributed to Pneumonia caused due to COVID19.However,the arterial blood gas showed metabolic acidosis with high anion gap. This was a non lactate acidosis with no hypoxemia. Most reasonably the state of pregnancy with increased energy demands along with increased metabolic maternal demand due to infection coupled with maternal starvation had resulted in this Ketoacidosis . In view of non progression of labor caesarian section was carried out and a healthy neonate was delivered. There was an initial improvement in maternal ketoacidosis post partum however optimal management of COVID19 pneumonia required oxygen support and use of corticosteroids. Thus we highlight how an unusual metabolic demands of pregnancy might mimic COVID 19.

COVID19 metabolic acidosis severe acute respiratory syndrome

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