Potential Antioxidant and Anti-Proliferative Activities of Biologically Active Marine Algae Extracts
Taha A. Kumosani, Khadijah Saeed Balamash, Hanaa Ghashlan, Youssri Ahmed Mohamed, Othman A. S. Baothman, Mustafa Zeyadi, Soonham Sami Yaghmoor, Areej H. Alyahiby, Rana R. AL-Rasheed, Wafa Y. Alturkistani, Tahani M. Alghamdi, Maryam H. AL-Zahrani, Said Salama Moselhy
Journal of Pharmaceutical Research International · pp. 1–7 · Published 30 Jul 2017
10.9734/JPRI/2017/38089Abstract
Background: Marine microorganisms such as algae were identified a rich sources of biologically active compounds. This study was designed to explore the in vitro antioxidant, anti-apoptotic and anti proliferative activities of different algae [Gracilaria dendroides (GD), Dictyota ciliolata (DC) and Cladophora socialis (CS)] extracts obtained from Red sea at Jeddah. Materials and Methods: Algae extracts (ethanol, chloroform and water) were tested for antioxidant activity for free radical scavenging and secondly as anti-apoptotic and anti-proliferative activity against different cell lines. Antioxidant capacity was detected by evaluation superoxide anion radicals, reducing potential and assay of phenolic and flavonoid content in extracts. Results: Chloroform extract of DC (CEDC) was found to have a better free radical scavenging activity (IC50= 310.58 g/ml) than methanol extract (MEDC). MEDC (IC50= 522 g/ml). The phenol level in CEDC and MEDC were 50.1 and 38.18 mg, while flavonoids were 65.58and 41.74 /mg.EDC and EDC were showed ant proliferative against MC7 and HALA 1. Conclusion: The solvents extracts exhibited promising biological activity as antioxidants and ant proliferative action.
Cited by 6
Imam A. Mekkawy, Usama M. Mahmoud, Rehab H. Moneeb · Frontiers in Marine Science · 2020
Ayşe Gül Tekbaba, Nisanur Kutlu, Alican Bahadır Semerci · Water, Air, & Soil Pollution · 2025
Rania F. Ismail, Norhan E. Saleh, Alaa El-Din H. Sayed · Environmental Science and Pollution Research · 2021
Gholamreza Bahrami, Babak Izadi, Seyed Shahram Miraghaee · Research in Pharmaceutical Sciences · 2021
Mohamed Mabrouk, Mohamed Ashour, Mohamed F. Abdelghany · Journal of Animal Physiology and Animal Nutrition · 2024
Marwa E. Hassan, Abo El-Khair B. El-Sayed, Mosaad A. Abdel-Wahhab · Environmental Science and Pollution Research · 2020
Related research
- In vitro Antioxidant and Anticancer Activity of Cyanobacteria — shares topic coverage
- Review: Parkia speciosa as Valuable, Miracle of Nature — shares topic coverage
- A Selective Review of Lipid Autoxidation and Rancidity, Antioxidants, and Dithiooxamide — shares topic coverage
- Antioxidant and Haemato-Biochemical Enhancing Properties of Daucus carota in Male Wistar Rats Toxicated with Lead Chloride — shares topic coverage
- Radical Scavenging Capacity and Efficacy of Myristica fragrans (Nutmeg) Metabolites on Cladosporum herbarum of Food Origin — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
6
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.