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Research Article Open access CC BY 4.0

IgA Nephropathy may be a Disease Related to Crohn's Disease

Gyong Hoon Kang, Sangeon Gwoo, Soo Young Kim, Joung Wook Yang, Ho Sik Shin, Ye Na Kim

Journal of Advances in Medicine and Medical Research · pp. 1–6 · Published 16 Jun 2015

10.9734/BJMMR/2015/17097

Abstract

IgA nephropathy (IgAN) is the commonest form of glomerulonephritis worldwide and 15–30% of patients will ultimately develop end-stage renal failure. IgAN can be primary (in most cases) or secondary (associated with seronegative arthritis, cirrhosis, coeliac disease, vasculitis, HIV), but is rarely associated with Crohn’s disease (CD). We describe a case of 22 year-old man with CD associated with IgAN. After the patient underwent surgical resection of right colon due to suspected colon tumor, CD was diagnosed. 5 years after right hemicolectomy, microscopic hematuria was developed and a renal biopsy had revealed IgAN (type III). Patients with CD who present with hematuria more commonly have urological complications, but the possibility of renal parenchymal disease should also be considered.

IgA nephropathy Crohn’s disease hematuria

Cited by 2

Immunoglobulin A nephropathy in association with inflammatory bowel diseases: results from a national study and systematic literature review

Nizar Joher, Clément Gosset, Dominique Guerrot · Nephrology Dialysis Transplantation · 2021

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