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Research Article Open access CC BY 4.0

Primary HIV Infection as an Unusual Cause of Neutropenia in Crohn’s Disease: A Case Report

Y. A. Awuku, S. R. Thomson, D. Levin, S. Hlashtwayo, G. Watermeyer

Journal of Advances in Medicine and Medical Research · pp. 1–4 · Published 28 Apr 2016

10.9734/BJMMR/2016/26166

Abstract

Although primary human immune deficiency virus (HIV) infection is a well described entity, it is frequently misdiagnosed or underdiagnosed. This has been attributed to the non-specific clinical features at presentation, inadequate history taking and a low index of suspicion by practicing clinicians. Haematological abnormalities are a recognised feature of HIV infection and may present in the form of pancytopenia or isolated cytopenias. One of the cardinal features of HIV seroconversion is leucopenia, however primary HIV infection as a cause of neutropenia and lymphopaenia in Crohn’s disease, has to our knowledge, not been described in the medical literature. We present a case of profound neutropenia in Crohn’s disease secondary to acute HIV sero-conversion illness.

Crohn’s disease neutropenia primary HIV infection HIV sero-conversion azathioprine

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