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Research Article Open access CC BY 3.0

Homotopy Perturbation Method for Solving Cell Cycle of Tumoural Cells

N. S. Ravindran, M. Mohamed Sheri, P. Krishnapriya

Journal of Advances in Mathematics and Computer Science · pp. 3271–3285 · Published 23 Sep 2014

10.9734/BJMCS/2014/12519

Abstract

In this work we present a mathematical model for tumour growth based on the biology of the cell cycle. Our model reproduces the dynamics of three different tumour cell populations: Quiescent cells, cells during the inter phase and mitotic cells. Here, we investigate the stability analysis of the cancer-free equilibrium. We have implemented Homotopy perturbation method to give approximated analytical solutions of non-linear ordinary differential equations of system such as model for Tumoural growth. A modification of the homotopy perturbation method based on the use of Pade approximations is done. Some plots are presented to show the reliability and simplicity of the methods.

Tumour Cell cycle Stability Homotopy perturbation method Pade approximation.

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