Evaluation of Hypolipidemic Potential of Aqueous Seed Extract of Moringa oleifera –An In vitro Study
Sariga Jayachandran, S. Kavitha, R. Gayathri, V. Vishnupriya, J. Selvaraj
Journal of Pharmaceutical Research International · pp. 2722–2729 · Published 26 Dec 2021
10.9734/jpri/2021/v33i60B34934Abstract
Introduction: Various parts of the tree Moringa oleifera Lam belonging to the Moringceae family are used extensively by the Indians as a major food constituent and also as herbal medicine. The dried seeds are used as a hypolipidemic agent for patients who suffer from obesity. Aim: The study was aimed at evaluation of hypolipidemic potential of aqueous seed extract of Moringa oleifera - an In vitro study. Materials and Methods: Hypolipidemic potential and antioxidant potential of aqueous seed extract of Moringa oleifera was analysed and compared with the standard drug. The data were statistically analyzed by one-way analysis of variance (ANOVA) followed by Duncan’s multiple range test and it was used to see the statistical significance among the groups. The results with the p<0.05 level were considered to be statistically significant. Results: The DPPH radical scavenging activity showed that the plant extract possessed a significant In vitro antioxidant( Ic50=220µg/ml) and hypolipidemic activity.(( Ic50=380µg/ml). Conclusion: The aqueous seed extract of Moringa oleifera exhibited a significant antioxidant and hypolipidemic potential.
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