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Research Article Open access CC BY 4.0

Effects of Botulinum Toxin (BoNT) and Factors on Weight Loss in Normotonic Pylorus (NP) and Hypotonic Pylorus (HP) Patients at Multivariate Level

Ismail Ozsan, Munevver Turanlı, Serdal Gunduz, Kadir Yılmaz

Asian Journal of Medicine and Health · pp. 48–55 · Published 27 Mar 2023

10.9734/ajmah/2023/v21i5815

Abstract

Background: In this retrospective research, it was aimed to evaluate effects of botulinum toxin (BoNT) and factors on weight loss in normotonic and hypotonic pylorus patients at multivariate level. Methods: A total of 671 patients attempted to our clinic between 2020 July to 2022 July were subjected to the study divided by two groups as NP (n=581) and HP (n=90). Results: Most of patients were female in both groups were females, but male rate in NP group was significantly higher (p<0.05). BMI, weight, weight difference and BMI difference means were significantly higher in NP group (p<0.05). Ursactive rate was significantly higher in HP group (p<0.05). Weight difference was significantly correlated with group (r=-0.267; p<0.01), gender (r=0.161; p<0.01), BMI (r=0.303; p<0.01), BMR (r=0.267; p<0.01), height (r=0.143; p<0.01), weight (r=0.328; p<0.01) and medicine usage (r=-0.082; 0.05). BMI difference was significantly correlated with group (r=-0.262; p<0.01), BMI (r=0.305; p<0.01), BMR (r=0.158; p<0.01) and weight (r=0.239; p<0.01). Generalized Linear Model (Logit Model) results showed that NP (B=3.497; p<0.01), BMI (B=0.342; p<0.01) and BMR (B=0.004; p<0.01) had significant contribution on weight difference. Conclusion: BoNT is more effective in normotonic pylorus patients than hypotonic pylorus for weight loss and BMI reduction. 

Botulinum toxin normotonic hypotonic pylorus

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