Botulinum Toxin: A Friend or an Enemy?
Archana Singh Sikarwar, Haw Tatt Jhong, Prema Mono Nair, Chin Yuee Teng, Ch’ngGim Khi, Phoon Mei Ee, YeakNai Teng, Iris Goh WenLi, Goh Hui San
Microbiology Research Journal International · pp. 61–70 · Published 15 Dec 2014
10.9734/BMRJ/2015/13907Abstract
Botulinum toxin is utilized in many drugs for the treatment purposes in healthcare. Besides healthcare, it is also utilized in the cosmetic industry. Botulism toxin is a very good friend as far as we use it with precaution and follow all guidelines for controlled doses for medication. Botulinum toxin is also known as Botulinum neurotoxin, which has been classified as seven serotypes, structurally similar but different in their antigenic and serological properties. Toxins are specific proteases, which act by degrading the protein component essential for exocytosis. BoNT/A is widely applied in neurological treatment as remodelling of neuromuscular junctions. Despite causing neuromuscular disease that could prove fatal, BoNTs are of great interest and may unveil their true potential in medical applications. They could become very useful and valuable research tools, which may lead to novel applications from cosmetic interventions to development of potent anti-cancer drugs.
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