Effects of Aqueous Seed Extracts of Sphenostylis stenocarpa on the Reproductive Indices of Male Rats
E. F. Ogbuke, D. E. Oboho, N. D. Ekpo, E. O. Mbong, A. U. Nelson, I. J. Udo, N. I. Etukudo, V. C. Ejere
Biotechnology Journal International · pp. 25–34 · Published 10 Mar 2023
10.9734/bji/2023/v27i1670Abstract
Effects of aqueous seed extracts of Sphenostylis stenocarpa on the reproductive indices of male rats were investigated. A total of 104 adult rats were used for the experiment, and were divided into 4 groups (group A – D) and replicated in triplicate. Group A served as the normal control, while groups B, C and D received three graded doses (800mg/kg, 1200mg/kg and 1600mg/kg) of the extracts, respectively, by oral intubation. The gonad characteristics, sperm parameters and hormonal analyses of the male rats were determined using standard procedures. These were ascertained prior to the commencement of treatment, and on weekly basis. Data were analyzed statistically using SPSS and R software at 95% confidence interval. An overall dose and time dependent showed significant differences in the mean weekly gonad characteristics of the male rats in the treatment groups when compared with the control. There was a significant reduction (p < 0.05) in the body weights of the male rats, but a significant increase (P < 0.05) in the testes weights, gonad somatic index, sperm count and sperm motility in the rats. The gonadal hormone testosterone, responded to the plant extracts, while follicle-stimulating and luteinizing hormones were largely undetected. There were significant increases in the testosterone levels of all the treated rats. Conclusively, aqueous seed extracts of Sphenostylis stenocarpa seems to possess ability to enhance reproductive health in male rats.
References (24)
- 1 A new approach to practical acute toxicity testing [DOI]
- 2 New Antimicrobials of Plant Origin
- 3 The prospects of African yam bean: past and future importance [DOI]
- 4 A Critical Review of Methods for Evaluation of Spermatogenesis from Seminal Characteristics [DOI]
- 5 From medical herbalism to phytotherapy in dermatology: back to the future [DOI]
- 6 Implication of reproductive endocrine malfunction in male antifertility efficacy of Azadirachta indica extract in rats.
- 7 Antifertility studies of Colebrookia oppositifolia leaf extract in male rats with special reference to testicular cell population dynamics [DOI]
- 8 Effect of alcoholic extract of Nigella sativa on fertility in male rats.
- 9 Reproductive evaluation of aqueous crude extract of Achillea millefolium L. (Asteraceae) in Wistar rats [DOI]
- 10 Morinda citrifolia Linn (Noni): In vivo and in vitro reproductive toxicology [DOI]
- 11 The effect of aqueous extract of gross and commercial yerba mate (Ilex paraguariensis) on intra-abdominal and epididymal fat and glucose levels in male Wistar rats [DOI]
- 12 Effect of heat treatment on the proximate composition, energy values, and levels of some toxicants in African yam bean (Sphenostylis stenocarpa) seed varieties [DOI]
- 13 Aqueous extract of Carpolobia lutea root ameliorates paroxetine-induced anti-androgenic activity in male rats [DOI]
- 14 Medicinal plants with potential anti-fertility activity: A review [DOI]
- 15 The nutritional potentials and possibilities in African yam bean for Africans.
- 16 Toxicological investigations on the methanol sub-fraction of the seeds of Carica papaya as a male contraceptive in albino rats [DOI]
- 17 Aqueous root extract of Lecaniodiscus cupanioides restores the alterations in testicular parameters of sexually impaired male rats [DOI]
- 18 An Evaluation of Toxicity and Mutagenicity of Sphenocentrum jollyanum [DOI]
- 19 Effect Of Germination On Proximate, Available Phenol And Flavonoid Content, And Antioxidant Activities Of African Yam Bean (Sphenostylis Stenocarpa) [DOI]
- 20 Evaluation of Anti-Obesity Potentials of Sphenostylis stenocarpa Ethanolic Seed Extract [DOI]
- 21 Effect of Germination on Proximate, Available Phenol and Flavonoid Content and Antioxidant Activities of African Yam Bean (Sphenostylis stenocarpa) [DOI]
- 22 In Vivo Models for Male Reproductive Toxicology [DOI]
- 23 African Journal of Pharmacy and Pharmacology [DOI]
- 24 INTERNATIONAL JOURNAL OF PHARMACOLOGY [DOI]
Cited by 0
No indexed citations yet.
Related research
- Effect of Cashew Kernel and Soya Bean Oils on Blood Serum Cholesterol and Triglyceride of Albino Rats (Rattus rattus) — shares topic coverage
- Effects of Eruca sativa Leaves Extracts on Testes, Fertility Potential and Testosterone Concentration in Male Rats — shares topic coverage
- Growth Performance of Albino Rats Fed Graded Levels of Baobab (Adansonia digitata) Leaf Meal — shares topic coverage
- Effect of Dietary Supplementation of Maize (Zea mays) with Soybean (Glycine max) and Moringa (Moringa oleifera) on Blood Biochemical Profile of Albino Rats — shares topic coverage
- Growth Performance of Albino Rats Orally Administered with Honey from Apis mellifera adansonii and Refined Sugar at Varying Levels — shares topic coverage
Article metrics
Real usage data collected on this platform.
6
Page views
0
PDF downloads
0
Outbound clicks
0
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.