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Research Article Open access CC BY 4.0

Correlation between Polycystic Ovary Syndrome and Periodontal Disease

Shamli Dhakulkar, Pavan Bajaj, Komal Bhombe

Journal of Pharmaceutical Research International · pp. 3679–3685 · Published 28 Dec 2021

10.9734/jpri/2021/v33i60B35062

Abstract

Background: Polycystic ovary syndrome has metabolic and reproductive properties that may be associated with periodontitis. The goal of this study was to reassess and offer a comprehensive critical evaluation of all findings associating Polycystic ovarian syndrome (PCOS) and PD, as well as to analyse a possible two - way relationship. The underlying molecular processes of this link are unknown, but chronic inflammation is considered to be a cause. A pro-inflammatory condition was linked to a changed periodontal response in PCOS, which appeared to enhance vulnerability to periodontal disease. Polycystic ovarian syndrome suffers more than half of all females of childbearing age., and has serious consequences for the metabolic, psychological, and cardiovascular systems. Inflammation is a characteristic sign of PCOS. There may be a role for chronic low-grade inflammation as well in metabolic abnormalities. Hence this review aims to correlate the association between PCOS and Periodontal Disease.

PCOS periodontal inflammation periodontal diseases cytokines metabolic syndromes

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