Controlled Release of Bi-Layered Delphinidin Tablets Using 3D Printing Techniques

Abstract

Delphinidin is a known dye and food colorant along with many medicinal properties for instance anti-inflammatory, anti-microbial, anti-diabetic, anti-obesity and anti-cancer. The present research has been designed to formulate bi-layered tablets using delphinidin which inherits these medicinal properties. The extrusion of tablets is done by using 3D printing techniques involving a table-top 3D printer which extrudes delphinidin tablets along with the required excipients. The characteristics of the whole tablets have been analyzed separately including hardness, friability, and weight. Adapted method for tablet formulation results in tablets which are appropriate for the immediate release and sustained release. The present research provides a method to make the effective tablets with reduced cost which can be used as drug formulation method in pharmaceutical industries.