Cerebrovascular Disease in Children with Sickle Cell Disease: Is There Any Need for Iron Therapy?
I. O. George, A. I. Frank-Briggs
International Blood Research & Reviews · pp. 1–5 · Published 13 Jul 2015
10.9734/IBRR/2015/18154Abstract
Background: Iron deficiency is a common problem affecting children world-wide. It has been recognized to have an association with stroke. The aim of this study was to evaluate the prevalence of iron deficiency anaemia among children with sickle cell anaemia with cerebrovascular accident and the need for iron therapy. Materials and Methods: All cases of cerebrovascular disease in children with sickle cell anaemia presenting in the department of Paediatrics of the University of Teaching Hospital were prospectively investigated for serum ferritin, haemoglobin, and MCV, MCHC and blood film. Results: A total of 152 children with sickle cell disease were seen during this period. One hundred and forty nine had HbSS genotype while 3 had HbSC genotype. Cerebrovascular disease was diagnosed in 7 patients giving a prevalence rate of 4.6%. Of these, 2(28.6%) had low serum ferritin levels (P=0.09) with hypochromia and microcytosis. Conclusion: Iron deficiency anaemia is not uncommon among sickle cell patients with cerebrovascular disease. There is need for elaborate iron study in these patients so as to identify at risk cases and institute prompt treatment.
Cited by 0
No indexed citations yet.
Related research
- Musculoskeletal Complications of Sickle Cell Anaemia and Their Management Approaches in Makurdi, Nigeria — shares topic coverage
- Sickle Cell Anaemia: A Prevalence Study among the Children Attending Usmanu Danfodiyo University Teaching Hospital, Sokoto, North-Western Nigeria — shares topic coverage
- Pulmonary Hypertension in Adults with Sickle Cell Anaemia: A Prevalence Study in the Niger Delta Region of Nigeria — shares topic coverage
- Prevalence and Predictors of Elevated Pulmonary Artery Pressure in Nigerian Children with Sickle Cell Anaemia — shares topic coverage
- L- Arginine and Nitric Oxide Levels among Children with Sickle Cell Disease in a Steady State in Federal Teaching Hospital Gombe, Northeastern Nigeria — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
0
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.