Evaluation of the Ex vivo and In vitro Antidiabetic and Antioxidant Activities of the Hydroalcoholic Extract of Psidium guajava L. Leaves (Myrtaceae)
Afangbom Kossi, Motto Aku Enam, MELILA Mamatchi, Atchou Kokou, Lawson-EVI Povi
Asian Journal of Biology · pp. 67–76 · Published 22 May 2024
10.9734/ajob/2024/v20i6416Abstract
Objective: Antidiabetic activity was assessed by the skeletal muscle glucose uptake test and antioxidant potential by the total antioxidant capacity, reducing power and DPPH test. Materials and Methods: Same-sex Sprague Dawley rats weighing 150±20 g and approximately 3 months old and different concentrations of the extract obtained from 500 g of P. guajava leaves powder were used for the following methods: reduction, free radical scavenging, glucose uptake by skeletal muscle. Results: In terms of antioxidant potential, the extract showed significant activity in a dose-dependent manner. In addition, the extract potentiated glucose uptake in the presence and absence of insulin. Compared with metformin and glibenclamide, the extract increased glucose uptake to a greater extent. Conclusion: This study shows that the hydroethanolic extract of guava leaves is one of the best recipes for helping to delay the complications associated with diabetes.
Cited by 0
No indexed citations yet.
Related research
- First Trimester Fasting Blood Glucose as a Screening Tool for Diabetes Mellitus in a Teaching Hospital Setting in Nigeria — shares topic coverage
- Impact of the Diet Profile and Alcohol Consumption on Cardiometabolic Risks in Dschang Health District-Cameroon — shares topic coverage
- Effect of Aqueous Extract of Persea americana Seed on Blood Glucose in Alloxan-induced Diabetic Wistar Rats — shares topic coverage
- Metal Based α-glucosidase Inhibitors: Synthesis, Characterization and α-glucosidase Inhibition Activity of Transition Metal Complexes — shares topic coverage
- Evaluation of Fluid Therapy by Point-of-Care Ultrasound in Hyperglycemic Emergencies — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
0
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.