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Research Article Open access CC BY 4.0

A Rare Case Report on Hirschsprung’s Disease

Pratibha Wankhede, Achal Gulghane, Mayur Wanjari

Journal of Pharmaceutical Research International · pp. 132–136 · Published 12 Oct 2021

10.9734/jpri/2021/v33i46A32849

Abstract

Introduction: Hirschsprung’s disease is a condition that affects the large intestine and causes problems passing stool. It was first identified by “Ruysch” in 1961 and popularized by Hirschsprung’s in 1886. A missing nerve cell in the baby's colon muscles causes the condition, which is present at birth. Clinical Findings: Difficulty in passing stool, Abdominal pain, fever, (Temperature 100-degree f) Vomiting, Failure to thrive, poor feeding. Diagnostic Evaluation: CBC Infestation, Blood test, Hb -10.4 gm%, Total RBC Count -4.37 million /cu mm, RDW-13.3%, HCT-30.5%, Total WBC Cont-4000 /cu mm, Monocytes- 13%, Granulocytes-65%, Lymphocytes-30%, AST (SGOT)-28 U/L. Therapeutic Intervention: Blood Transfusion, Inj. Aminoven 200 mg BD, Cefotaxime 400 mg BD IV, Inj. Amikacin 130 mg OD, Inj. Metrogyl 90 mg BD, Inj. Pantocid 10 mg OD. Outcome: After Treatment the child show improvement in his passing stool frequently and relived Vomiting, fever, and increases feeding pattern. Conclusion: My patient was admitted to pediatric ward no 22 at AVBRH with a known case of Hirschsprung's Disease, and he had complained of difficulty in passing stool, at birth after getting appropriate treatment and surgery his condition was improving.

Hirschsprung’s disease congenital megacolon intestinal aganglionosis enteric nerves system congenital aganglionosis megacolon

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