Aims: Misuse of antimicrobial medicines is a major contributory factor to development of resistant strains of micro-organisms, therapeutic failure and increased healthcare costs in many countries. To identify pattern of antimicrobial use among undergraduate students of the Univer...
Open access
Research Article10.9734/BJPR/2014/5972
Objective: To evaluate the role of anti-depressants (Duloxetine) and NSAID (Dexibuprofen) in a new rat model of chronic induced depression. Methods: Twenty four male wistar rats were divided into 4 groups of 6 animals each. Group I to IV served as vehicle control, osteoarthritis...
Open access
Research Article10.9734/BJPR/2014/4040
Aims: The leaves of Gmelina arborea (ROXB.) (Family Verbenaceae) are widely used in the folklore to treat various types of diseases. In this study, the antioxidant and cytotoxic activities of different methanolic extracts and the derived subfractions of 90% methanolic extract of...
Open access
Research Article10.9734/BJPR/2014/6018
Aims: Sequel to the resurgence of TB co-infection in HIV/AIDS patients in sub-Saharan Africa, efavirenz has become an important component of the highly active antiretroviral treatment (HAART). The objective of this study therefore is to provide a simple reversed-phase high perfor...
Open access
Research Article10.9734/BJPR/2014/4123
Objectives: To evaluate possible ocular hypotensive effect of 0.5% diltiazem and 0.1% verapamil eye drops on intraocular pressure in steroid induced glaucoma model of rabbits. And compare with 0.5% timolol eye drops. Methodology: Glaucoma was induced in rabbits (N=18) by bilatera...
Open access
Research Article10.9734/BJPR/2013/4389
The effect of paraquat on Clarias gariepinus (220.50 ± 15.33g mean weight and 30.43 ± 1.22cm mean total length) was examined by the assessment of the organ indices and haematological parameters after twenty one days of exposure. It was observed that paraquat caused decline in the...
Open access
Research Article10.9734/BJPR/2013/3647
Aim: The present study was undertaken to evaluate the antidiabetic effects of the Tamarindus indica Linn seed in normal (non-diabetic), type-I and type-II model rats and to investigate their effect on gastrointestinal motility and intestinal glucose absorption. Methodology: T. in...
Open access
Research Article10.9734/BJPR/2013/4865
Aims: The purpose of this research is to develop a novel expandable gastroretentive dosage form (GRDF), based on unfolding mechanism. It consists of a drug loaded bilayer polymeric film, folded into a hard gelatin capsule. Gastric retention is achieved due to unfolding of the dos...
Open access
Research Article10.9734/BJPR/2013/4891
Aims: To formulate and characterize GLB-PEG-LEC NCs (lecithin complexed Glibenclamide nanocrystals) and to analyze the effect of PEG 20000 and lecithin on drug properties, particle size reduction and stability of GLB NCs. Study Design: Precipitated (GLB-PEG) and complexed nanocry...
Open access
Research Article10.9734/BJPR/2013/5515
Aims: Hiptage benghalensis is used in the traditional system of medicine. The leaf is considered one of the important plant organs for the treatment of various diseases such as rheumatism, leprosy, wounds, ulcer, burning sensation, scabies, inflammation and cough. Hence, the pres...
Open access
Research Article10.9734/BJPR/2013/4454