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Journal of Pharmaceutical Research International

Published by SCIENCEDOMAIN international · ISSN (electronic) 2456-9119

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7,450

Articles indexed

84

2026 articles

7,450

Open access

23,857

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Articles (7450)

Formulation and Evaluation of Vaginal Bioadhesive Drug Delivery System of Acyclovir

Bhaskar Mohite, Rakesh Patel & Nandu Kayande · Journal of Pharmaceutical Research International · 2021

Acyclovir is an anti-viral, which has been used in the treatment of vaginal disorder. Acyclovir is almost completely absorbed after oral administration but has low bioavailability of about 10-15% because of first pass metabolism. As first pass metabolism removes approximately 85-...

Open access Research Article 10.9734/jpri/2021/v33i45A32723

Preclinical Screening of Antidepressant Activity of Formulated Sertraline Hydrochloride-Loaded Solid Lipid Nanoparticles in Rats

Sachin R. Hangargekar, Pradeep K. Mohanty & Janki Prasad Rai · Journal of Pharmaceutical Research International · 2021

Objective: The main goal of our study was to investigate the antidepressant activity of Formulated Sertraline hydrochloride-loaded Solid Lipid Nanoparticles (SLNPs) by using a rat forced swimming test (FST) and tail suspension test (TST). Materials and Methods: Animals were divid...

Open access Research Article 10.9734/jpri/2021/v33i45A32725

Stability-indicating RP-UPLC Method for Determination of Vildagliptin in Drug Substance and Its Tablet Dosage Form

Kalyani Peluri & S. Rajasekaran · Journal of Pharmaceutical Research International · 2021

Aim: The foremost purpose of this research work is to diminish the analysis time and to establish cost effective method for estimation of Vildagliptin by RP-UPLC. Study Design: UPLC based Quantification studies. Place and Duration of Study: Department of Pharmacy, Bhagwant Univer...

Open access Research Article 10.9734/jpri/2021/v33i45A32726

Normal Reference Range for Serum TSH, Free T4, Total T4, and Total T3 on Roche® Platforms in Basrah, Iraq

Nassar Taha Alibrahim, Samih Abed Odhaib, Ali Hussain Alhamza, Ammar Mohammed Saeed Almomin, Ibrahim Abbood Zaboon, Rudha Naser Hussein, Muayad Baheer Kadhim, Adel Gassab Mohammed, Dheyaa Kadhim Al-Waeli, Hussein Ali Nwayyir, Haider Ayad Alidrisi, Ibrahim Hani Hussein, Mahmood Thamer Altemimi, Husam Jihad Imran & Abbas Ali Mansour · Journal of Pharmaceutical Research International · 2021

Background: Thyroid function tests are mandatory in clinical practice because symptoms and signs are not reliable to discriminate between various types of thyroid disease. Aim: The aim of this study was to determine assay-specific reference range for serum free T4, total T4, tota...

Open access Research Article 10.9734/jpri/2021/v33i45A32727

A Comparative Study on Isolation and Characterization of Lecithin from Gallus gallus and Gallus Domesticus Using Analytical Methods

S. F. Choragudi, N. Sibin, M. Keerthi Padma Sree, Gulam Saleem, K. Prashanth Babu & C. H. Arun · Journal of Pharmaceutical Research International · 2021

The present study mainly focuses on the extraction and purification of lecithin from both Gallus gallus and Gallus gallus domesticus. The comparative study shows a great significance in the amount and quality of lecithin extracted from both the sources. The egg lecithin was stand...

Open access Research Article 10.9734/jpri/2021/v33i45A32729

Effect of Muscle Energy Technique versus Motor Control Exercise Adjunct to Conventional Therapy on Pain, Range of Motion and Functional Disability in Patients with Chronic Neck Pain – A Research Protocol

Deepak Jain, Deepali Patil & Pratik Phansopkar · Journal of Pharmaceutical Research International · 2021

Background: Physical, neuropathic, or secondary causes can all contribute to neck difficulty. Any other illness might be acute 6 weeks, subacute 3 months, or chronic (lasting more than 6 weeks) (lasting up to three months). Physical consequences, life-distressing or non-life- dis...

Open access Research Article 10.9734/jpri/2021/v33i45A32714

Role of Vitamin (D) Deficiency in Children with Autism Spectrum Disorder

Mohammed Hussen Sheikh, Manal Mohammed E. Alhawiti, Shaykhah Salman A. Alderaan, Daher Mushref Daher Alshehri, Shahad Abdulaziz S. Alzahrani, Aseel Ali T. Albalawi, Reem Awadh N. Alharbi, Faisal Ibrahim S. AlSukairan, Hamad Saad M. Alkhaldi, Zainab Ali H. Alarab, Abdullah Hassan F. Alsuayri & Marwan Fahad H. Altemani · Journal of Pharmaceutical Research International · 2021

The disorder of the automatic spectrum is a neurodolevating disorder characterized by a decrease in social interactions, communication and stereotypical disorders and repeated behaviors with various degrees of gravity. A number of systematic reviews and meta- analyses have descri...

Open access Research Article 10.9734/jpri/2021/v33i45A32713

Efficacy of Integrated Neuromuscular Inhibition Technique Versus Mulligan Mobilization on Pain and Functional Disability in Subjects with Non-Specific Low Back Pain –A Research Protocol

Neha Chitale, Deepali Patil & Pratik Phansopkar · Journal of Pharmaceutical Research International · 2021

Introduction: Pain in lower back region is a problem everyone deals with at least once in their life. Chronic back pain in lower back region is the pain which is present for more than 3 months. We can divide lower back pain as specific back pain or non-specific back pain. Non-spe...

Open access Research Article 10.9734/jpri/2021/v33i45A32719

Premilinary Phytochemical Study of Different Extracts of One Medicinal Plant Cissus quadrangularis

Saranya Arunagiri & K. S. Srinivasan · Journal of Pharmaceutical Research International · 2021

Herbal plants are the most valuable resources to prevent from many illness and to treat the many disorders in humans. Cissus quadrangularis is a one of the traditional medicine and belonging to vitaceae family. In Ayurvedha medicinal system this plant is used to treat many diseas...

Open access Research Article 10.9734/jpri/2021/v33i45A32712

Dietary Supplementation of Lactobacillus brevis Normalizes Metabolic Parameters in Mouse with Obesity and Hyperglycemia

Amlan Jyoti Ghosh, Rejuan Islam & Tilak Saha · Journal of Pharmaceutical Research International · 2021

Aims: Exploration of the ameliorative effects of Lactobacillus brevis on glycemic and obesity parameters in high fat diet (HFD) fed hyperglycemic Swiss albino mice. Study Design: HFD with 58% fat, 25.6% carbohydrate, and 16.4% protein was fed to mice to develop metabolic syndrome...

Open access Research Article 10.9734/jpri/2021/v33i45A32715