Gagging reflex poses a hurdle in numerous dental procedures. It causes discomfort for the patient, extended procedure time for the clinician, compromised quality of treatment and along with a lot of physiological discomfort for both. The normal gag reflex is protective in nature,...
Open access
Research Article10.9734/jpri/2021/v33i46B32937
Hisham Mohammed Sonbul, Mohammed Ali Mohammed Alqahtani, Abdullah Mohammed Bajebair, Ali Abdallah A. Aljameely, Saud Ali Aloudah, Mohammed Ali M. Alshamrani & Fayez Abdulaziz A Alharthi·Journal of Pharmaceutical Research International·2021
According to WHO statistics, over 300,000 people die each year by burns, and more dying from electric burns, scalds or other causes of burns. Burn injuries and wounds are typically fatal. And they can cause serious long-term implications for victims. The most important aspect in...
Open access
Research Article10.9734/jpri/2021/v33i46B32940
Background: Based on ayurvedic/folklore medicine majority of the medicinal plants are used for treatment of different ailments. Sophora interrupta as traditional medicine focused to do the research work for protection of renal injury. Aim: The present study was investigated the n...
Open access
Research Article10.9734/jpri/2021/v33i46B32929
Aims: This study aims to test the antioxidant activity of red and purple H. sabdariffa flower petals extract and conduct qualitative phytochemical screening. Study Design: Antioxidant potential of red and purple H. sabdariffa flower petal extract analyzed by spectrometric assays....
Open access
Research Article10.9734/jpri/2021/v33i46B32931
Colon cancer is a tumor of the large intestine. It is the third most common cause of cancer-related death in the United States. However, most people with colon cancer get better if the cancer is found early. The atherogenic index of plasma (AIP), triglyceride-glucose (TyG) index,...
Open access
Research Article10.9734/jpri/2021/v33i46B32935
Umida Khamidova, Ekaterina Terenteva, Mukaddas Umarova, Jaloliddin Abdurakhmanov, Sabirdjan Sasmakov, Artyom Makhnyov, Valentina Vinogradova, Abdusalom Saidov, Zaynat Khashimova & Shakhnoz Azimova·Journal of Pharmaceutical Research International·2021
A row of 1-alkyne (C6-C17) derivatives against tetrahydroisoquinoline have been synthesized. 1-alkyne (C6-C17) derivatives cytotoxicity against three lines of cancer cells and two lines of normal cells was studied. It was found that 1-tridecyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoq...
Open access
Research Article10.9734/jpri/2021/v33i46B32938
Background: Long term intake of high amount of fluoride leads to fluorosis causing metabolic, functional and structural damages affecting many tissues and organs including dental and skeletal manifestations. The liver is the most susceptible organ to fluoride toxicity because of...
Open access
Research Article10.9734/jpri/2021/v33i46B32939
Aims: The aim of present study was to develop a stomach specific formulation of Imatinibmesylate to increase the fraction of drug absorbed in stomach. Study Design: Development and Optimization of Microspheres for site specific delivery.. Place and Duration of Study: The study wa...
Open access
Research Article10.9734/jpri/2021/v33i46B32941
Infertility is a serious issue disturbing reproductive ages in all society now and calling for solution for continuity. Infertility were induced on groups of animals with separate sexes; M, M1, M2 and M3; F, F1, F2 andF3 with daily subcutaneous administration of 20 mg/kg body wei...
Open access
Research Article10.9734/jpri/2021/v33i46B32942
Farkhod Eshboev, Elvira Yusupova, Galina Piyakina, Sabirdjan Sasmakov, Jaloliddin Abdurakhmanov, Shuhrat Khasanоv, Oybek Ashirov, Sherali Kuziev, Durdona Toshpulatova & Shakhnoz Azimova·Journal of Pharmaceutical Research International·2021
Drug addiction is one of the biggest problems of medicine because diagnosis and treatment of drug addiction are difficult compared with some other socially significant diseases. In this study, synthesis and evaluation of four carrier protein-morphine conjugates were experimented....
Open access
Research Article10.9734/jpri/2021/v33i46B32943