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Journal of Pharmaceutical Research International

· ISSN (electronic) 2456-9119

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175

Articles indexed

0

2026 articles

175

Open access

559

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Articles (175)

Potential Antioxidant and Anti-Proliferative Activities of Biologically Active Marine Algae Extracts

Taha A. Kumosani, Khadijah Saeed Balamash, Hanaa Ghashlan, Youssri Ahmed Mohamed, Othman A. S. Baothman, Mustafa Zeyadi, Soonham Sami Yaghmoor, Areej H. Alyahiby, Rana R. AL-Rasheed, Wafa Y. Alturkistani, Tahani M. Alghamdi, Maryam H. AL-Zahrani & Said Salama Moselhy · Journal of Pharmaceutical Research International · 2017

Background: Marine microorganisms such as algae were identified a rich sources of biologically active compounds. This study was designed to explore the in vitro antioxidant, anti-apoptotic and anti proliferative activities of different algae [Gracilaria dendroides (GD), Dictyota...

Open access Research Article 10.9734/JPRI/2017/38089

Effect of Levetiracetam in the Treatment of Refractory Seizure in Infants through EEG: The Case of the Neonatal Intensive Care Unit of Tehran’s Children’s Medical Center

Malihe Kadivar, Mahboobeh Mohammadi, Ziba Mosayebi, Reza Shervinbadv, Raziee Sangsari & Bahram Yarali · Journal of Pharmaceutical Research International · 2017

Objective: Phenobarbital, phenytoin and Benzodiazepins are the most common treatments for resistant neonatal seizure [1]. Drug of choice in the treatment of neonatal seizure should be more effective and have fewer side effects. This study examines the effect of Levetriacetam (LEV...

Open access Research Article 10.9734/JPRI/2017/33922

Assessment of Antibiotic Self-medication Pattern among University Students in Eastern Democratic Republic of the Congo

Gabriel Kambale Bunduki, Mupenzi Mumbere & François Katsuva Mbahweka · Journal of Pharmaceutical Research International · 2017

Background: Self-medication with antibiotics has been reported among university students in many countries, but no study has been conducted on this issue in Democratic Republic of the Congo (DRC). Aim: This study aimed to assess the knowledge and behaviours of university students...

Open access Research Article 10.9734/JPRI/2017/31848

The Role of Aripiprazole (An Anti-psychotic Drug) in the Resolution of Acute Peripheral Inflammation in Male Wistar Rats

L. D. Adedayo, D. A. Olawuyi, A. O. Ojo, O. Bamidele, S. A. Onasanwo & A. O. Ayoka · Journal of Pharmaceutical Research International · 2017

Aripiprazole, a known second generation anti-psychotic drug has been implicated to possess an anti-inflammatory potential, but yet not scientific adequately explored. This study investigated the role of aripiprazole in the resolution of acute peripheral inflammation in male wista...

Open access Research Article 10.9734/JPRI/2017/32601

Assessment of Anti-atopic Dermatitis Activity of Oroxylum indicum Extract Incorporated Cream

Do Hoang Thu Trang & Hoang Le Son · Journal of Pharmaceutical Research International · 2017

Aims: The search for plant-based treatments against atopic dermatitis (AD), a relapsing dermatological condition with high prevalence in tropical regions, has always been attracting special attention. Among many folk remedies for AD, Oroxylum indicum Linn (Bignoniaceae) is a comm...

Open access Research Article 10.9734/JPRI/2017/34325

Garlic (Allium sativum L.) Protects Hepatic and Renal Toxicity of Alloxan in Rats

J. S. Aprioku & F. S. Amah-Tariah · Journal of Pharmaceutical Research International · 2017

Aims: Allium sativum (Garlic) possesses antioxidant principles and is consumed widely as a nutritional agent and for medicinal purposes. This work investigated the effects of aqueous Garlic bulb extract on alloxan-induced plasma elevations of hepatic enzymes and renal biochemical...

Open access Research Article 10.9734/JPRI/2017/34909

Synthesis of Some Novel Semicarbazone and Thiosemicarbazone Derivatives of Isatin as Possible Biologically Active Agents

Masoumeh Divar, Ali Khalafi-Nezhad, Kamiar Zomorodian, Razieh Sabet, Zahra Faghih, Maryam Jamali, Hasti Pournaghz & Soghra Khabnadideh · Journal of Pharmaceutical Research International · 2017

Aims: The development of new beneficial agents is one of the crucial aims in medicinal chemistry. Isatin is considered as a vital class of bioactive compounds exhibiting different biological activities. A series of nine new Semicarbazone (12a-i) and six new Thiosemicarbazone (14a...

Open access Research Article 10.9734/JPRI/2017/35243

Nephroprotective Effect of Phoenix reclinata Total Crude Root Extract on Tenofovir Induced Kidney Damage in Wistar Albino Rats

Cissy B. Namuleme, Kokas Ikwap, Andrew Tamale, Gabriel Tumwine, John Kateregga & Charles D. Kato · Journal of Pharmaceutical Research International · 2017

Tenofovir (TDF), used in combination with other antiretroviral agents, is an effective therapy for HIV infection. However, prolonged use of this drug is limited by a life threatening nephrotoxicity. Phoenix reclinata is a common palm species native to tropical Africa and is commo...

Open access Research Article 10.9734/JPRI/2017/34247

Performance Optimization of Sustained Release Arginine Alginate Microbeads with a Natural Polysaccharide

Ritesh Kumar Tiwari, Lalit Singh & Vijay Sharma · Journal of Pharmaceutical Research International · 2017

Objectives: The design of effective and safe novel drug delivery systems has become an integral part for the development and formulating of new medicines. So, research continuously keeps on searching for new ways to deliver drugs over a long period of time or for a well-controlle...

Open access Research Article 10.9734/JPRI/2017/34305