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Journal of Pharmaceutical Research International

· ISSN (electronic) 2456-9119

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175

Articles indexed

0

2026 articles

175

Open access

469

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Articles (175)

Antifungal, Antioxidant and Phytochemical Screening of Melia azedarach Flower Extracts by Using Different Solvents

Muhammad Khawar Abbas, Mahmood Ahmad, Kashif Barkat & Naila Aslam · Journal of Pharmaceutical Research International · 2017

Objective: To investigate the antifungal, antioxidant and phytochemical screening of Melia azedarach flowers by using different solvents. Materials and Methods: Antifungal activity was experimented against three fungi (Aspergillus niger, Aspergillus fumigatus, Aspergillus flavus)...

Open access Research Article 10.9734/JPRI/2017/38246

QSAR Pharmacophore-based Virtual Screening, CoMFA and CoMSIA Modeling and Molecular Docking towards Identifying Lead Compounds for Breast Cancer Protease Inhibitors

Lan Huang, Xuan R. Zhang, Pei H. Luo, Lun Yuan, Xang Z. Zhou, X. Gao & Ling S. Li · Journal of Pharmaceutical Research International · 2017

Aim: This study used QSAR Pharmacophore-based virtual screening and molecular docking to identify lead compounds and determine structural requirements for breast cancer inhibitor development. CoMFA and CoMSIA modeling was employed to design more potential inhibitors. Materials an...

Open access Research Article 10.9734/JPRI/2017/37821

Antibacterial Activity of Ocimum gratissimum L. against Some Selected Human Bacterial Pathogens

Ajose Daniel Jesuwenu & Okozi Ogheneoremume Michael · Journal of Pharmaceutical Research International · 2017

Aim: This study was designed to investigate the bioactive spice to determine its activity against some selected human bacterial pathogens. The spice studied was Ocimum gratissimum (clove basil). Place and Duration of study: Microbiology laboratory of Bells University of Technolog...

Open access Research Article 10.9734/JPRI/2017/37897

Design and Evaluation of a New Fixed-Dose Immediate Release Capsule of Atenolol, Enalapril Maleate and Hydrochlorothiazide

Nickania A. Pryce, Amusa S. Adebayo, Deon A. Bennett & Eugenie Brown-Myrie · Journal of Pharmaceutical Research International · 2017

Aim and Objectives: To design, formulate and perform in vitro studies of a fixed dose combination (FDC) immediate release solid dosage form of the antihypertensive drugs atenolol, enalapril and hydrochlorothiazide. The objectives of the study were to perform pre-formulation studi...

Open access Research Article 10.9734/JPRI/2017/38019

Investigate the Effect of Fatty Acids on Rheological Properties and In vitro Permeability of Escitalopram Oxalate from Hydroxypropyl Cellulose Gel Formulations

Nisarg Modi, Marina Borovinskaya, Fotios Plakogiannis & Rutesh Dave · Journal of Pharmaceutical Research International · 2017

The present studies evaluate rheological properties and in-vitro permeability properties of Escitalopram Oxalate (ECO) containing hydroxypropyl cellulose (Klucel HF, HPC) gels prepared with different carbon chain length containing fatty acids. The formulations were prepared by mi...

Open access Research Article 10.9734/JPRI/2017/37901

In vitro Antiglycation, Antioxidant and Antiproliferative Properties of Peptides Derived from Tryptic Hydrolysis of Soya Bean

Abudukadeer Kuerban, Said S. Moselhy, Hanaa Ghashlan, Taha A. Kumosani, Othman A. S. Baothman, Mustafa Zeyadi, Nawal Helmi, Tahani M. Alghamdi, Mazin A. Zamzami, Muqtadir Baig Mirza, Fareeduddin Quadri Syed, Furkhan Ahmed Mohammed, Abdulrahman L. AL-Malki & Khalid O. Abulnaja · Journal of Pharmaceutical Research International · 2017

Aims: Bioactive peptides are acknowledged for their vital contributions to health promotion. This study aims to evaluate antiglycation, antioxidant and antiproliferative ability of peptides derived from tryptic hydrolysis of Soya bean. Place and Duration of Study: Department of B...

Open access Research Article 10.9734/JPRI/2017/37636

Pharmacist Perceived Barriers to Patient Counseling; A Study in Eastern Region of Saudi Arabia

Fatima Zuhair Al Laif, Rizwan Ahmad, Atta Abbas Naqvi & Niyaz Ahmad · Journal of Pharmaceutical Research International · 2017

Background: Pharmaceutical care model (PCM) is the philosophy of practice that includes identifying and resolving medication therapy problems to improve patient outcomes. Patient counseling by a pharmacist is a fundamental step in health care practice, as it allows the patients t...

Open access Research Article 10.9734/JPRI/2017/37705

Phytochemical and Biological Evaluation of R. hastatus and R. himalyica (Polygonaceae) from Galiyat Pakistan

Sophia Awais, Irshad Ahmad, Syed Saeed Ul Hassan, Hammad Yousaf & Juwairiya Butt · Journal of Pharmaceutical Research International · 2017

The medicinal plants have been known for their wide variety of applications for centuries. R. hastatus and R. himalyica are such medicinal plants which have been used in Ayurveda for their excellent antioxidative and scavenging properties. The present study is designed to explore...

Open access Research Article 10.9734/JPRI/2017/37143

Cosmeceutical Benefit of Abelmoschus esculentus L. Seed Extract

Sirikhwan Manee & Jasadee Kaewsrichan · Journal of Pharmaceutical Research International · 2017

Background: Abelmoschus esculentus L. or okra is a vegetable of Malvaceae family. Aim: Okra seeds were dried at 60°C, ground, and extracted by using absolute ethanol. The acquired extract was investigated for chemical constituents, cytotoxicity, anti-tyrosinase activity, and anti...

Open access Research Article 10.9734/JPRI/2017/37587

Spoilage Bacteria Associated with Selected Body Lotions Commonly Used amongst Students of the University of Port Harcourt, Nigeria

Emmanuel Ezenna, H. O. Stanley & C. N. Stanley · Journal of Pharmaceutical Research International · 2017

The study investigated the spoilage bacteria associated with selected body lotions commonly used amongst students of the University of Port Harcourt. The influence of the body lotion on the bacterial composition of the skin was also determined. Five in- use lotions were obtained...

Open access Research Article 10.9734/JPRI/2017/33478