The objective of this research was to studying the antibacterial activity of Portulaca oleracea L. in vitro cultures. P. oleracea leaves were collected from the local markets. Callus tissues were induced from the plant leaves (expalnt) through inoculating the explants on MS mediu...
Open access
Research Article10.9734/JPRI/2017/36071
The past few decades have seen a tremendous growth in the use of microneedles in the transdermal delivery of therapeutics. This is due to the several advantages that microneedles offer in the delivery of compounds. Therapeutics are delivered in a simple, minimally invasive and pa...
Open access
Research Article10.9734/JPRI/2017/36164
Aim: A new simple reversed phase high performance liquid chromatographic method was developed for the estimation of Atezolizumab in bulk and its injectable formulation. Study Design: Quantitative and qualitative estimation and degradation studies of AZM by using Rp-HPLC. Place an...
Open access
Research Article10.9734/JPRI/2017/35615
Senna occidentalis has been used in traditional medicine in Nigeria for managing various ailments in traditional medicine. This study was aimed at evaluating the central nervous system depressant effect of ethanol leaf extract of Senna occidentalis in mice. Thirty mice of either...
Open access
Research Article10.9734/JPRI/2017/25432
The present review describes biological activities of semi- and synthetic epithio steroids. About fifty biologically active compounds have shown confirmed antitumor, immunosuppressant, or aromatase inhibition and other activities. More than a quarter of all studied steroids belon...
Open access
Research Article10.9734/JPRI/2017/36199
The problem of antibiotic resistance is fast becoming a pandemic which has necessitated the need for new drugs discovery. This study was carried out to screen two green algal species- Bryopsis pennata andChaetomorpha anteninna for antibacterial activity against multidrug resistan...
Open access
Research Article10.9734/JPRI/2017/35924
The present review describes the biological activities of synthetic nitro steroids. More than fifty biologically active nitro steroids showed an analeptic, antineoplastic, anesthetic, neuroprotector, immunosuppressant, dermatologic properties, and also show other biological activ...
Open access
Research Article10.9734/JPRI/2017/36196
Nasrin Bahmani, Mohammad Reza Arabestani, Seyed Hamid Hashemi, Abbas Farahani, Reza Mirnejad, Parviz Mohajeri, Manoochehr Karami & Mohammad Yousef Alikhani·Journal of Pharmaceutical Research International·2017
Background: The Brucellosis is recognized as a significant public health problem, with major economic and financial burdens in countries where the disease remains endemic. The disease is one of the most important worldwide zoonosis affecting livestock and humans. The aim of the p...
Open access
Research Article10.9734/JPRI/2017/34911
The aim of this study was to evaluate the effects of fermented soya bean supplements on thyroid profile and serum electrolytes of high fat diet-induced type 2 diabetes in rabbits. Twenty rabbits weighing between 1 kg – 1.5 kg were used for the study. Diabetes was induced by feedi...
Open access
Research Article10.9734/JPRI/2017/35680
Mahrukh Yousaf, Usama Asif, Khurram Aamir, Inaam-ur-rehman ., Sehrish Haider, Afzaal Bashir, Furqan K. Hashmi, Mohamed Azmi Hassali & Zikria Saleem·Journal of Pharmaceutical Research International·2017
Background: Chronic myelogenous leukemia (CML) is potentially curable disease of white blood cells (WBCs) especially granulocytes. Our objective was to evaluate comparative efficacy and safety of two chemotherapy protocols i.e. hyper-CVAD and MEC in patients with CML who were unr...
Open access
Research Article10.9734/JPRI/2017/35631