Rita Nkiru Ajirenike, Amaewhule Mary Nnneda, Dasetima D. Altraide, Figilo Ibeinmo Moses, Amadi Ekechi Stella, Johnson Mine & Ogbu Christian.·International Research Journal of Oncology·2024
Kaposi sarcoma (K.S) is a rare type of cancer with four clinical variants which has a link to Human Herpes Virus (HHV-8) in the etiology. Commonly seen are the acquired immunodeficiency syndrome (AIDS) -related variants. Kaposi Sarcoma occurring after solid-organ transplant is a...
Samuel Chukwuemeka Okenwa, Lazarus Chukwuemeka Ejike, Ifunanya Genevieve Anunwa, Jane Chidera Nwachukwu, Wisdom Joe Igbokwe, Henry Chiagozie Igwenagu, Emmanuel Buchi Onyioha, Joel Chekwube Ugwuezea & Chika Augusta Ekweozor·International Research Journal of Oncology·2024
Background: Cancer is currently a global health issue and has claimed the lives of many. Cancer used to be a previously more prevalent in high-income countries, but at the moment, 75% of new cancer cases could be from low and middle income countries (LMIC). Healthcare workers pl...
Colorectal cancer (CRC) is the third most common cancer worldwide, remains a major cause of cancer-related morbidity and mortality globally. It has diverse treatment modalities including chemotherapy, immunotherapy, and targeted therapies. Chemotherapy remains a cornerstone of CR...
Lung cancer remains the leading cause of cancer-related death globally, with non-small cell lung cancer (NSCLC) accounting for most cases. A critical subset of NSCLC is characterized by anaplastic lymphoma kinase (ALK) gene rearrangements, which drive tumor growth and progression...
Tucatinib is a highly selective tyrosine kinase inhibitor targeting the HER2 protein, representing a significant advancement in treating HER2-positive metastatic breast cancer (MBC), including cases with brain metastases. This review assesses the efficacy and safety of tucatinib...
Background: Advancements in research and technology have expanded the array of available cancer treatment options. Nonetheless, these treatments may adversely impact the overall health of patients. The specific influence of each treatment option or their combined effects on cance...
Bloodstream infections (BSIs) caused by Gram-negative bacteria (GNB) are a significant concern in patients with hematological malignancies (HM), particularly when multidrug-resistant (MDR) strains are involved. This review synthesizes key findings from studies investigating the e...
Background: Social media platforms have become indispensable tools for communication and information exchange, playing an increasingly significant role in the healthcare landscape. Within the realm of cancer care, these platforms provide valuable avenues for accessing information...
Fidelis Godae Beega, Kemzi Elechi-Amadi, Simeon Christopher Aloy, Sheudeen Abubakar Abiola, Okorocha, CyrilGentle Ugochukwu, Ibioku Elekima & Edna Ogechi Nwachuku·International Research Journal of Oncology·2024
While naturally occurring, heavy metals pose a significant global public health risk due to their extensive utilisation in industrial, residential, and agricultural activities, impacting the health of millions worldwide. Occupational and environmental exposure to these metals thr...
Cytotoxic chemotherapy was a tragic by-product of World War II. It was the major therapeutic modality employed but failed to win the War on Cancer during 1971-1976 declared by President Nixon. Despite the failure, killing of cancer cells (CCs) remained the commanding principle of...