Lawrence John AJutor, Olutayo Nathanael Farinde, Edibokun Theresa Orobator, Toluwanimi Janet Kolapo, Izuchukwu Gerald Ezema, Victor Damilare Oladele, Tobi David Farinde, Adedapo Olosunde, Peace Godwin Monday & Ayomide Babatunde Ishola·International Research Journal of Oncology·2025
Non-small cell lung cancer (NSCLC) is regarded as the most prevalent form of lung cancer, accounting for approximately 85% of all cases worldwide. This type of cancer is highly affected by the tumour microenvironment (TME), where exosomal communication is a major contributor. Thi...
Open access
Research Article10.9734/irjo/2025/v8i1173
RabaahALadawya Mohammed SalihElbasheri Gadkreem, Hassan Yousif Adam Regal, Ekhlas Alrasheid Abuelfadol, GaleelaAbdalgader Salem, AwadEljeed Abugooda Alobaid, Ahmed Abdalla AgabEldour & Hussain Gadelkarim Ahmed·International Research Journal of Oncology·2025
Background: Lymphoma is a type of cancer that originates in the lymphatic system, which is a crucial part of the body’s immune system. According to the World Health Organization (WHO), lymphoma is classified morphologically, immunophenotypically and genetically into Hodgkin lymph...
Open access
Research Article10.9734/irjo/2025/v8i1171
Akhaine J. Precious, Onu S. Ngozi, Dongo E. Naomi, Ayemoro O. Temitope, Oiku M. Omofuma, Ananwuna P. Nnagozie, Lebechi N. Opara, Madu, W. Chimezie, Okeke O.Daniel, Ighodaro T. Osazuwa, Ogedegbe S. Idemudia & Ozigbo F. Oziegbe·International Research Journal of Oncology·2025
Introduction: Breast cancer is a growing menace to the world, especially in developing West Africa countries such as Nigeria. Its incidence in Nigeria has been rising and yet so many cases remain undocumented especially due to poor reportage and late presentation. A number of iss...
Open access
Research Article10.9734/irjo/2025/v8i1172
Lawrence John AJutor, Blessing Aitebiereme Iyoyojie, Kingsley Ugonna Ugoagwu, Orkaa Terungwa Samuel, Olufemi Adesola Adedayo, Daniel Temiloluwa Oyedemi, Daniel Ebubechi Obasi, Adegbesan Abiodun Christopher, Adewoyin Peter Bemigho & Christian Ajiri Adobor·International Research Journal of Oncology·2025
Triple-negative breast cancer (TNBC) is one of the most prominent types of breast cancer. It is a very aggressive subtype that is characterized by the absence of certain receptors which are expected on the surface of tumor cells. Limited treatment options and a poor prognosis, hi...
Open access
Research Article10.9734/irjo/2025/v8i1170
Background: Primary adenoid cystic carcinoma (ACC) of breast is rarely seen clinically. It is a special subtype of triple-negative breast cancer characterized by low expression of Ki-67, low malignant potential, slow progression and favourable prognosis. To date, treatment for th...
Open access
Research Article10.9734/irjo/2025/v8i1169
Immunotherapy has emerged as a transformative approach in cancer treatment, yet its efficacy is often limited by interpatient variability and immune resistance mechanisms. Recent advances suggest that nutritional status and dietary interventions can significantly influence the im...
Open access
Research Article10.9734/irjo/2024/v7i2168
Background: T-PLL is a rare T cell Chronic Lymphoproliferative disorder (T-CLPD), representing about 2% of mature lymphocytic leukaemia in adults over age of 30 years, with a median diagnosis age of 65 years. It commonly presents with symptoms like hepatosplenomegaly, generalized...
Open access
Research Article10.9734/irjo/2024/v7i2167
Jane Nkechi Nwafor, Taiwo A Falaiye, Olubukola Anike Kuye, Simbiat Quadri Eniola, Ehireme Anne Osarenkhoe-Ighodaro, Kelechi Ethelbert Oguzie, Okelue E. Okobi & Maurice Puomaaye Konta·International Research Journal of Oncology·2024
Primary care plays a vital role in cancer patients' early detection, referral, and ongoing management. This systematic review explores how primary care providers (PCPs) facilitate early diagnosis, ensure continuity of care, and support patients throughout their cancer journey and...
Open access
Research Article10.9734/irjo/2024/v7i2165
Fenny Halim, Slamet Isworo, Enny Rachmani, Teguh Suryanto, Fitri Amalia, Grestaliansa Indira & Muhammad Faiq Malik Al Hakim·International Research Journal of Oncology·2024
Background and Objective: The management of Papillary Thyroid Carcinoma (PTC) is influenced by factors such as patient age and clinical characteristics. However, the clinical features of PTC in adolescents (ages 10-19) have not been widely studied. Adolescents may present unique...
Open access
Research Article10.9734/irjo/2024/v7i2166
Soft tissue tumors are a diverse range of diagnostic entities including the majority of them benign in nature and behavior. Soft tissue sarcomas are uncommon tumors that represent 1% of all malignancies and are classified as malignant entities. The wide variety of tumor types and...