J. Sunitha Blessy, Flowrence Evangelin Kona, Rokkam Vanya Sri, Harathi Kovvuri, M. John Winkle, Soujanya Ferdinand, B. Bhavani & K. Padmalatha·International Research Journal of Oncology·2026
Cancer treatment has undergone a profound transformation over the past two decades, evolving from non-specific cytotoxic chemotherapy toward precision-based targeted therapies and immunotherapeutic strategies. Advances in molecular oncology have enabled the identification of onco...
Open access
Research Article10.9734/irjo/2026/v9i1193
Introduction: Ovarian cancer is one of the most lethal gynecological malignancies and is often referred to as the “silent killer” due to the absence of specific symptoms in its early stages. Late detection contributes to high mortality rates globally. This study aimed to assess w...
Open access
Research Article10.9734/irjo/2025/v8i2192
Background: Head and Neck Squamous Cell Carcinoma (HNSCC) accounts for a substantial proportion of cancer cases globally and represents a significant contributor to cancer-related morbidity and mortality, particularly in India. The global incidence of HNSCC is steadily increasing...
Open access
Research Article10.9734/irjo/2025/v8i2191
Introduction: Mantle cell lymphoma (MCL) is a rare and aggressive form of B-cell non-Hodgkin lymphoma, representing 5%-7% of cases, with a median age at diagnosis around 65 years. Historically, MCL was considered incurable, with chemotherapy offering only temporary remission. Rec...
Open access
Research Article10.9734/irjo/2025/v8i2190
Objective: To present a case report of ovarian spindle cell neoplastic lesions with sex cord stromal differentiation, highlighting diagnostic challenges in the absence of immunohistochemistry (IHC). Methods: Clinical, radiological, surgical, and histopathological data were review...
Open access
Research Article10.9734/irjo/2025/v8i2189
Salvation Ifechukwude Atalor, Jumoke Ologun, Modinat Aina, Abayomi, Obiageri Ihuarulam Okeoma, Opeoluwa Alayande, Awah Favour Matthew, Reginald Oyortey & Lawrence John AJutor·International Research Journal of Oncology·2025
Gene editing technologies have revolutionized the approach to treating cancer by enabling precise modifications to the genome, particularly through programmable chromosome engineering techniques that allow for large-scale rearrangements, deletions, and insertions to correct or di...
Open access
Research Article10.9734/irjo/2025/v8i2187
Background: Fibrocystic breast changes (FBC), a common benign condition affecting up to 50% of reproductive-age women, often present with mastalgia and nodularity. While medical management is first-line, surgical excision is considered for refractory cases. Aim: This single-centr...
Open access
Research Article10.9734/irjo/2025/v8i2188
Background: In 2022 alone, the World Health Organisation estimated that breast cancer caused 670000 deaths globally. Breast cancer is a significant public health concern worldwide. It is a disease in which abnormal breast cells grow out of control and form tumours. It is the main...
Open access
Research Article10.9734/irjo/2025/v8i2186
Oluwatobiloba Kehinde Adedokun, Temitope Emmanuel Alo, Kazeem Olanrewaju Bankole, Modinat Aina, Abayomi, Nanmet Ephraim Panwal, Jeremiah Tella & Lawrence John AJutor·International Research Journal of Oncology·2025
While genetic mutations are well-known triggers for leukaemia, inflammation plays a big part by messing with cell growth and immune responses, yet its complex patterns are hard to track with traditional methods. This review looks at how artificial intelligence (AI) and machine le...
Open access
Research Article10.9734/irjo/2025/v8i2185
Lymphedema is a chronic, progressive condition of the lymphatic system characterized by inflammation, fibro adipose tissue deposition, and impaired lymphatic drainage. Lingual lymphedema, in particular, poses unique challenges due to the critical role of the tongue in oral motor...
Open access
Research Article10.9734/irjo/2025/v8i2184