This study describes a comparison between blood and urine profiles of Remogliflozin simultaneously in a rat pharmacokinetic study using a simple UPLC method. Quantitative determination of Remogliflozin is performed in rat blood with the recovery values in the range of 85-115%. A...
The Term undifferentiated connective tissue disease is used to define conditions characterised by the presence of signs and symptoms suggestive of a systemic autoimmune disease that does not satisfy the classification criteria for defined connective tissue diseases (CTD) such as...
Introduction: Diabetic nephropathy is a leading cause of end-stage renal failure and chronic kidney disease throughout the globe. Despite the fact that much research has been conducted in both basic science and clinical therapeutics to better understanding of the biology of diabe...
Background: Diabetes mellitus (DM) is a chronic condition requiring global attention. Renal microangiopathy is a life-threatening microvascular complication often leading to derangements in renal function and progressive renal failure. Renal haemodynamic assessment by duplex Dopp...
Eleki Beniboba Jenewari, Briggs Datonye Christopher, Membere Ibinabo, Nonju Tamunobarabiye Ibifubara, Okachi Elageche Wesley & Peterside Michael Philip·Asian Journal of Research in Nephrology·2023
Introduction: In Nigeria, the occurrence of kidney disease is on the rise and prevention is key. Disease awareness is low, yet knowledge of kidney in disease and health is an essential preventive measure. Information on the knowledge of the kidney, disease prevention and therapeu...
Adeyemi Abiola Adefidipe, Akinwunmi Komolafe, Bamikefa Titilope, Kayode Adelusola, Adegoke Aremu & Fatiu Arogundade·Asian Journal of Research in Nephrology·2023
Background: Nephrotic syndrome is one of the major ways in which kidney disease presents clinically the world over. Where biopsies are carried out, the microscopic appearances observed in the affected patients vary according to age, gender, race and geographical location. In most...
Taofeeq Oduola, Muhammed K. Dallatu, Zayyanu U. Umar, Fatimah O. Mazai, Miftahu Bello, Khadijat O. Oduola, Ibrahim B. Isah & Makusidi A. Muhammad·Asian Journal of Research in Nephrology·2022
Background: Glucose-6-phosphate dehydrogenase deficiency has been implicated in the pathogenesis of a number of common diseases, including acute kidney injury. G6PD deficient individuals are prone to developing acute kidney injury if exposed to certain medication, food or infecti...
Adedeji Okikiade, Nourhan Abdulrahman, Miriam Tikanide, Jeffrey Ndu, Annah Akoth, Esther Akinyode, Twanna Browne-Caesar & Aromedonghene Osharode·Asian Journal of Research in Nephrology·2022
Alport syndrome (AS), also known as hereditary nephrosis, is an X-linked genetic disease that predominantly affects type IV collagen mainly in the kidneys and the eyes. It primarily affects males, particularly children, and can be transmitted via autosomal dominant and recessive...
Background: Iron deficiency is common in Nepal due to low socioeconomic reason in pre-dialysis chronic kidney disease (CKD) patients than in the hemodialysis population. Little is known about the iron indices in CKD patients in Nepal. Aim: The aim of this study was to evaluate th...
M. M. Sulaiman, I. Chiroma, A. A. Ndahi, A. D. Dayar, U. Loskurima, J. Shettima, M. Lawan, A. Mamza, A. J. Turajo & I. Ummate·Asian Journal of Research in Nephrology·2022
Introduction: Diabetic Diabetes mellitus is a chronic metabolic disorder of carbohydrates, lipids and protein resulting from absolute or relative lack of insulin. The myriad of metabolic derangements lead to development of complications such as DKD. Insulin deficiency is the comm...