Cadmium chloride exposure is associated with oxidative stress and structural injury in tissues, including endocrine organs. This study evaluated the protective effect of oral L-arginine against cadmium chloride-induced toxicity in the adrenal glands of adult male Wistar rats. Twe...
Open access
Research Article10.9734/ajrn/2026/v9i1130
Background: Autosomal dominant polycystic kidney disease (ADPKD) has a heterogeneous clinical course, and clinical, biochemical, and imaging characteristics are important for assessing disease burden and progression risk. Aims: This study aimed to describe these characteristics i...
Open access
Research Article10.9734/ajrn/2026/v9i1129
Cadmium is a pervasive environmental toxicant with a long biological half-life, and the kidney, owing to its high blood flow and filtration role, is particularly vulnerable to cadmium-induced injury characterised by oxidative stress, tubular necrosis, and fibrosis. Annona muricat...
Open access
Research Article10.9734/ajrn/2026/v9i1127
Background: Acute kidney injury (AKI) is a common and serious complication among patients with type 2 diabetes mellitus (T2DM), contributing significantly to morbidity, mortality, prolonged hospitalisation, and progression to chronic kidney disease (CKD). Data on the epidemiology...
Open access
Research Article10.9734/ajrn/2026/v9i1128
Chronic kidney disease (CKD) is a progressive multisystem condition with a growing global burden that may be compounded by circadian disruption and irregular dietary patterns. Chrononutrition, which examines the interaction between meal timing and circadian rhythms, remains under...
Open access
Research Article10.9734/ajrn/2026/v9i1126
Diabetes mellitus (DM) is one of the most common causes and comorbidities in chronic kidney disease (CKD) globally. Particularly, DM in CKD patients increases the overall risk for kidney failure, atherosclerotic cardiovascular disease, heart failure, and premature mortality. Rece...
Open access
Research Article10.9734/ajrn/2026/v9i1125
Konstantinos S. Mavromatidis, Gioulia V. Romanidou, Athanasios V. Bakaloudis, Anastasia K. Georgoulidou & Panagiota M. Zinapi·Asian Journal of Research in Nephrology·2026
Metabolic alkalosis is maybe the most common and serious acid-base disorder in clinical practice (the life of any patient with pH>7.55 is at serious risk). It is accompanied by hypochloremia and hypokalemia. Its most common cause is the use of diuretics, the use of which is qu...
Open access
Research Article10.9734/ajrn/2026/v9i1123
Fousiya Yoonus, E. K. Jayakumar, K. S. Sajeev Kumar, Krishna Suresh, V. Unnikrishnan Ramachandran, Nishita Mohan Philip, Dina Clerin Francis & Avin Alex·Asian Journal of Research in Nephrology·2026
GLP 1 agonists have evolved into one of the most potent weapons in the arsenal to tackle diabetes and metabolic disease, while providing significant cardiorenal outcomes, as cemented by the FLOW trial. Their pleiotropic action extends into spheres of immune regulation, alleviatio...
Open access
Research Article10.9734/ajrn/2026/v9i1124
Background: The growing disparity between the demand for kidney transplantation and the availability of suitable grafts has prompted expansion of living donor acceptance criteria. Objective: To evaluate the feasibility and safety of ex vivo stone clearance in living donor kidneys...
Open access
Research Article10.9734/ajrn/2026/v9i1122
Introduction: Urinalysis is a useful screening tool that provides a simple, cost-effective, and non-invasive method for assessing kidney function and early detection of kidney involvement in HIV patients with or without antiretroviral therapy. The use of highly active antiretrovi...
Open access
Research Article10.9734/ajrn/2026/v9i1121
Background: Pregnancy is associated with significant physiological changes in renal function, which influence the interpretation of biochemical markers. However, population-specific data on renal biomarkers and derived indices among pregnant women in sub-Saharan Africa remain lim...
Open access
Research Article10.9734/ajrn/2026/v9i1120
Agu Uchenna Francis, Ani, Celestine Okafor, Ejim Nnamdi Ferdinand, Uzoigwe Jide Uzowulu, Uzoefuna Casmir Chima, Agbor Joseph Ikenna, Ezinwa Anthony Chijioke & Nweke Luke Maduka·Asian Journal of Research in Nephrology·2026
Background: Nephrotoxicity remains a major clinical challenge, particularly in patients undergoing chemotherapy with agents such as doxorubicin (DOX). Doxorubicin-induced renal damage is largely mediated through oxidative stress, inflammation, and tubular epithelial cell injury,...
Open access
Research Article10.9734/ajrn/2026/v9i1119
Chronic kidney disease (CKD) is a major global public health challenge, affecting hundreds of millions of adults worldwide. The Global Burden of Disease 2023 study estimated that approximately 788 million adults aged 20 years and older were living with CKD in 2023. This study eva...
Open access
Research Article10.9734/ajrn/2026/v9i1118
Introduction: The glomerular filtration formulae are important in staging and determining renal function in HIV patients, and in the general population at large. Aim: The main objective of this study is to evaluate the performance of Chronic Kidney Disease Epidemiology Collaborat...
Open access
Research Article10.9734/ajrn/2026/v9i1117
Abdulrahman Abdullahi Ishag, Eiman Abdelrahman Elamin, Abdelwaged Abdelrahman Omer, Malaz Abdulazim Musa & Farah Riyad Gafar·Asian Journal of Research in Nephrology·2026
Background: The demographic and etiological landscape of Acute Kidney Injury (AKI) varies significantly across regions, influenced by local disease burdens and healthcare access. Data on AKI characteristics from Sudan and similar sub-Saharan African settings are scarce. This stud...
Open access
Research Article10.9734/ajrn/2026/v9i1116