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Uloaku Ogbuagu

Publications (28)

Effect of Ethanol Extract of Xylopia aethiopica Fruit on Oxidative Stress Indices of Wistar Rats

Emmanuel O. Ogbuagu, Uloaku Ogbuagu, Augustine I. Airaodion, Chika L. Uche, Edmund O. Ezirim, Ifeoma N. Nweke & Prince C. Unekwe · Asian Journal of Immunology · 2022

Background: The use of Xylopia aethiopica fruit in folklore medicine is on the increase without caution of its toxicity. Aim: This present study tends to assess its effect on the oxidative stress biomarkers of Wistar rats. Methodology: The fruits of Xylopia aethiopica were air-dr...

Open access Research Article

Qualitative Determination of the Phytochemical Composition of Ethanolic Extract of Xylopia aethiopica Fruit

Emmanuel O. Ogbuagu, Uloaku Ogbuagu, Prince C. Unekwe, Ifeoma N. Nweke & Augustine I. Airaodion · Asian Journal of Medical Principles and Clinical Practice · 2020

Aim: The aim of this study is to qualitatively determine the phytochemical compositions of ethanolic extract of Xylopia aethiopica fruit. Methodology: The fruits of Xylopia aethiopica were obtained from new market in Aba, Abia State and were identified and authenticated by Prof....

Open access Research Article

Ethanolic Extract of Xylopia aethiopica (African Negro Pepper) Fruit Adversely Perturbed Semen Qualities in Male Wistar Rats

Emmanuel O. Ogbuagu, Augustine I. Airaodion, Uloaku Ogbuagu, Edmund O. Ezirim, Ifeoma N. Nweke & Prince C. Unekwe · International Journal of Research and Reports in Gynaecology · 2022

Aim: This study was designed to assess the effect of Xylopia aethiopica fruit on the sperm qualities of male Wistar rats. Methodology: The fruits of Xylopia aethiopica were air-dried and extracted by Soxhlet extractor using ethanolic as solvent. The median lethal dose (LD50) of t...

Open access Research Article

Nephrotoxicity of Ethanol Extract of Xylopia aethiopica Fruit in Wistar Rats

Emmanuel O. Ogbuagu, Augustine I. Airaodion, Uloaku Ogbuagu, Ifeoma N. Nweke & Prince C. Unekwe · International Journal of Advances in Nephrology Research · 2021

Background: The use of Xylopia aethiopica fruit in folklore medicine is on the increase without regard to its toxicity. Aim: This study was aimed at examining its toxicity on the kidney of Wistar rats. Methodology: The fruits of Xylopia aethiopica were air-dried and extracted usi...

Open access Research Article

Histopathological Evaluation of Organs of Male Wistar Rats Fed with Monosodium Glutamate Treated-diet

Emmanuel O. Ogbuagu, Augustine I. Airaodion & Uloaku Ogbuagu · International Research Journal of Gastroenterology and Hepatology · 2019

Background: Recently, the use of seasonings to enhance the flavour of food has increased. A variety of seasonings are produced nowadays and the constituents of these flavour-enhancers are unknown to ignorant consumers. Most consumers preferred to eat food with good taste without...

Open access Research Article

Effect of Methanolic Extract of Vernonia amygdalina Leaves on Glycemic and Lipidaemic Indexes of Wistar Rats

Emmanuel O. Ogbuagu, A. I. Airaodion, Uloaku Ogbuagu & Edith O. Airaodion · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2019

Aim: This study sought to investigate the effect of methanolic extract of Vernonia amygdalina leaves on glycemic and lipidaemic indexes of Wistar rats. Methods: Fresh plants of V. amygdalina were harvested from the Institute of Agricultural Research and Training, Ibadan. The leav...

Open access Research Article 10.9734/ajrimps/2019/v7i330122

Hepatoprotective Effect of Parkia biglobosa on Acute Ethanol-induced Oxidative Stress in Wistar Rats

Augustine I. Airaodion, Emmanuel O. Ogbuagu, Uloaku Ogbuagu, Adenike R. Adeniji, Aanu P. Agunbiade & Edith O. Airaodion · International Research Journal of Gastroenterology and Hepatology · 2019

Aim: This study is aimed at investigating the hepatoprotective effect of Parkia biglobosa on acute ethanol-induced oxidative stress in wistar rats. Methods: P. biglobosa was purchased from a local market at Orita-Challenge area of Ibadan, Nigeria. They were sun dried and milled i...

Open access Research Article

Comparative Assessment of Phytochemical Content and Antioxidant Potential of Azadirachta indica and Parquetina nigrescens Leaves

Augustine Ikhueoya Airaodion, Peace Olaoluwa Olatoyinbo, Uloaku Ogbuagu, Emmanuel O. Ogbuagu, Joanne Dada Akinmolayan, Olukunle Abraham Adekale, Olaide Oladimeji Awosanya, Aanu Paul Agunbiade, Abiodun Paul Oloruntoba, Olajumoke Oluwaseun Obajimi, Adenike Rebecca Adeniji & Edith Oloseuan Airaodion · Asian Plant Research Journal · 2019

Aim: The aim of this study is to compare the phytochemical content and antioxidant potential of Azadirachta indica and Parquetina nigrescens leaves. Study Design: This study was made to fit a one way Analysis of Variance. Place and Duration of Study: This research was carried out...

Open access Research Article 10.9734/aprj/2019/v2i330045

Xylopia aethiopica Fruit Increased Prothrombin Time, Activated Partial Thromboplastin Time and Erythrocyte Sedimentation Rate of Wistar Rats

Emmanuel O. Ogbuagu, Augustine I. Airaodion, Chika L. Uche, Uloaku Ogbuagu, Edmund O. Ezirim, Prince C. Unekwe & Ifeoma N. Nweke · International Journal of Research and Reports in Hematology · 2022

Background: Traditionally, the use of Xylopia aethiopica fruit for therapeutic purposes is on the increase without any consideration of its safety and toxicity. Aim: This study was therefore designed to examine its effect on coagulation factors of Wistar rats. Methodology: The fr...

Open access Research Article

Alterations in Female Reproductive Hormones of Wistar Rats Sequel to the Administration of Xylopia aethiopica Fruit

Emmanuel O. Ogbuagu, Augustine I. Airaodion, Chika L. Uche, Uloaku Ogbuagu, Edmund O. Ezirim, Ifeoma N. Nweke & Prince C. Unekwe · Asian Research Journal of Gynaecology and Obstetrics · 2022

Aim: This present study was designed to examine the impact of Xylopia aethiopica fruit on the reproductive hormones of female Wistar rats. Methodology: The fruits of Xylopia aethiopica were air-dried and extracted by Soxhlet extractor using ethanol as solvent. The lethal dose of...

Open access Research Article

Effect of Monosodium Glutamate on Body Weight and Alanine Aminotransferase Activity in Wistar Rats

Emmanuel O. Ogbuagu, Augustine I. Airaodion, Victor N. Okoroukwu, Uloaku Ogbuagu & John A. Ekenjoku · International Research Journal of Gastroenterology and Hepatology · 2019

Background: In recent days, the use of seasonings to enhance the flavor of food has been increased. A variety of seasonings are produced now days and the constituents of these flavor-enhancers are unknown to ignorant consumers. The consumers were preferred to eat food with good t...

Open access Research Article

Hyperglycemic and Hypocholesterolemic Effect of Monosodium Glutamate in Wistar Rats

Emmanuel O. Ogbuagu, Augustine I. Airaodion, Victor N. Okoroukwu & Uloaku Ogbuagu · International Journal of Research and Reports in Hematology · 2019

Background: The use of seasonings to enhance the flavor of food has been on the increase in recent times. Different types of seasonings are produced daily and the constituents of these flavor-enhancers are unknown to ignorant consumers. They only want to eat food with good taste...

Open access Research Article

Ameliorative Efficacy of Phytochemical Content of Corchorus olitorius Leaves against Acute Ethanol-induced Oxidative Stress in Wistar Rats

Augustine I. Airaodion, Emmanuel O. Ogbuagu, Ogbonnaya Ewa, Uloaku Ogbuagu, Olaide O. Awosanya & Olukule A. Adekale · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2019

Aim: This study is aimed at investigating the ameliorative efficacy of methanolic extract of Corchorus olitorius leaves against acute ethanol-induced oxidative stress in Wistar rats. Methods: Fresh plants of C. olitorius were harvested from the Institute of Agricultural Research...

Open access Research Article 10.9734/ajbgmb/2019/v2i230054

Effect of Oral Intake of African Locust Bean on Fasting Blood Sugar and Lipid Profile of Albino Rats

Augustine I. Airaodion, Edith O. Airaodion, Emmanuel O. Ogbuagu, Uloaku Ogbuagu & Etinosa U. Osemwowa · Asian Journal of Research in Biochemistry · 2019

Background: African locust bean is a condiment believed to be for the people of low class. Its health importance has not been fully known especially to the so-called high class. Aim: This study is aimed at investigating the effect of African locust bean on fasting blood sugar and...

Open access Research Article 10.9734/ajrb/2019/v4i430073

Assessment of Bread in Ogbomoso Metropolis for the Presence of Potassium Bromate

Augustine I. Airaodion, Olaide O. Awosanya, Emmanuel O. Ogbuagu, Uloaku Ogbuagu, Onyinyechi C. Njoku, Chimdi Esonu & Edith O. Airaodion · Asian Journal of Research in Biochemistry · 2019

Aim: This study is aimed at evaluating the level of potassium bromate in bread in Ogbomoso metropolis. Study Design: This study was made to fit a one way Analysis of Variance (ANOVA). Place and duration of Study: The bread samples were purchased in Ogbomoso metropolis and analyze...

Open access Research Article 10.9734/ajrb/2019/v4i230065

Evaluation of Potassium Bromate in Bread in Ibadan Metropolis: Fifteen Years after Ban in Nigeria

Augustine I. Airaodion, Ogbonnaya Ewa, Emmanuel O. Ogbuagu, Uloaku Ogbuagu, Aanu P. Agunbiade & Abiodun P. Oloruntoba · Asian Food Science Journal · 2019

Background: In 2003, the National Agency for Food, Drug Administration and Control (NAFDAC), the agency responsible for regulating drugs, foods and chemicals in Nigeria, banned the use of potassium bromate in bread on account of its deleterious effect and carcinogenicity in human...

Open access Research Article 10.9734/afsj/2019/v7i429976

Hepatotoxic effect of Xylopia aethiopica Fruit in Wistar Rats

Emmanuel O. Ogbuagu, Prince C. Unekwe, Augustine I. Airaodion, Ifeoma N. Nweke & Uloaku Ogbuagu · International Research Journal of Gastroenterology and Hepatology · 2021

Background: Xylopia aethiopica fruit has been reported to possess high medicinal value. Thus, people use it without any regard for its toxicity. Aim: This study is therefore aimed at investigating its toxicity on the liver of Wistar rats. Methodology: The fruits of Xylopia aethio...

Open access Research Article

Weight Gain Reduction and Hypoglycemic Effects of Xylopia aethiopica Fruit Extract on Wistar Rats

Emmanuel O. Ogbuagu, Ifeoma N. Nweke, Prince C. Unekwe, Augustine I. Airaodion & Uloaku Ogbuagu · International Journal of Research and Reports in Hematology · 2021

Aim: This study is aimed at determining the effect of Xylopia aethiopica fruit on weight gain and blood sugar level of Wistar rats. Methodology: The fruits of Xylopia aethiopica were obtained from new market in Aba, Abia State, Nigeria and were authenticated. They were air-dried...

Open access Research Article

Hypolipidemic Propensity of Ethanolic Extract of Xylopia aethiopica Fruit in Wistar Rats

Emmanuel O. Ogbuagu, Prince C. Unekwe, Augustine I. Airaodion, Ifeoma N. Nweke & Uloaku Ogbuagu · Asian Journal of Research in Cardiovascular Diseases · 2021

Aim: This study is aimed at assessing the effect of Xylopia aethiopica fruit on the lipid profile of Wistar rats. Methodology: The fruits of Xylopia aethiopica were obtained from new market in Aba, Abia State, Nigeria and were authenticated. They were air-dried and extracted usin...

Open access Research Article

Bigi Soft Drinks might Induce Hyperglycemia and Hyperlipidemia in Wistar Rats

Augustine I. Airaodion, Emmanuel O. Ogbuagu, John A. Ekenjoku, Victor N. Okoroukwu & Uloaku Ogbuagu · International Journal of Research and Reports in Hematology · 2019

Background: Bigi soft drinks are carbonated drinks produced by Rite Foods Limited. The company is an indigenous company in Nigeria. Before 2016, Coca-cola bottling company and 7up bottling company products were the dominant soft drinks in Nigeria. Rite Foods Limited introduced ca...

Open access Research Article

Carica papaya Leaves Might Cause Miscarriage

Augustine I. Airaodion, John A. Ekenjoku, Emmanuel O. Ogbuagu, Victor N. Okoroukwu & Uloaku Ogbuagu · Asian Research Journal of Gynaecology and Obstetrics · 2019

Background: The use of Carica papaya leaves in folklore medicine for its antimalarial and antidiabetic activities is on the increase globally. Aim: This was undergone to investigate if C. papaya leaves have the propensity to induce miscarriage during pregnancy. Methods: Fresh and...

Open access Research Article

Oral Administration of Ethanolic Leaf Extract of Vernonia amygdalina May Impact Negatively on Fertility in Male Wistar Rats

John A. Ekenjoku, Augustine I. Airaodion, Victor N. Okoroukwu, Emmanuel O. Ogbuagu & Uloaku Ogbuagu · Asian Journal of Medical Principles and Clinical Practice · 2019

Background: The use of Vernonia amygdalina leaves as vegetables and in folklore medicine for therapeutic activities is on the increase globally. Aim: This study, therefore, sought to investigate the antifertility effect of V. amygdalina leaves in male Wistar rats. Methods: Fresh...

Open access Research Article

Effect of Methanolic Extract of Corchorus olitorius Leaves on Hypoglycemic and Hypolipidaemic Activities in Albino Rats

Augustine I. Airaodion, Joanne D. Akinmolayan, Emmanuel O. Ogbuagu, Edith O. Airaodion, Uloaku Ogbuagu & Olaide O. Awosanya · Asian Plant Research Journal · 2019

Aim: This study sought to investigate the hypoglycemic and hypolipidaemic effect of methanolic extract of Corchorus olitorius leaves in Albino rats. Methods: Fresh plants of C. olitorius were harvested from the Institute of Agricultural Research and Training, Ibadan. The leaves w...

Open access Research Article 10.9734/aprj/2019/v2i430054

Efficacy of Combined Crude Extract of Curcuma longa and Moringa oleifera in the Prevention of Peptic Ulcer in Albino Rats

A. I. Airaodion, Olukunle A. Adekale, Edith O. Airaodion, Emmanuel O. Ogbuagu, Uloaku Ogbuagu & Etinosa U. Osemwowa · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2019

Aim: This study is aimed at investigating the prophylactic efficacy of combined extract of Curcuma longa and Moringa oleifera leaf against indomethacin–induced ulcer in albino rats. Place and Duration of Study: This research was carried out in Ibadan Nigeria between November 2017...

Open access Research Article 10.9734/ajrimps/2019/v7i230115

Nutritional and Anti–Nutritional Evaluation of Garri Processed by Traditional and Instant Mechanical Methods

Augustine I. Airaodion, Edith O. Airaodion, Ogbonnaya Ewa, Emmanuel O. Ogbuagu & Uloaku Ogbuagu · Asian Food Science Journal · 2019

Aim: The aim of this study is to evaluate the nutritional and anti-nutritional composition of garri processed by traditional and instant mechanical methods. Place and Duration of Study: This study was carried out in Achara, Uturu and analyses were done at the Biochemistry and Cen...

Open access Research Article 10.9734/afsj/2019/v9i430021

Quality Assessment of Sachet and Bottled Water in Ogbomoso Metropolis, Nigeria

Augustine I. Airaodion, Edith O. Airaodion, Etinosa U. Osemwowa, Emmanuel O. Ogbuagu & Uloaku Ogbuagu · Asian Food Science Journal · 2019

Background: Access to potable water has become a difficult task in many countries of the world including Nigeria. In Nigeria, the government is trying her best to make water supply available to the masses but till now this vision has never been accomplished. If those living in ur...

Open access Research Article 10.9734/afsj/2019/v9i230007

Implication of Sugar Intake in Haemorrhoid and Menstruation

Augustine I. Airaodion, Peace R. Adejumo, Onyinyechi C. Njoku, Emmanuel O. Ogbuagu & Uloaku Ogbuagu · International Journal of Research and Reports in Hematology · 2019

This review discusses the implication of sugar intake in haemorrhoid and menstruation. Haemorrhoid is the clustering of veins in the rectum leading to swollen anus. This occurs due to pressure exerted on the rectum. When these veins swell, they expand outward into the membranes a...

Open access Research Article

Antifertility Propensity of Jatropha curcas Linn. Leaves on Male Wistar Rats

Augustine I. Airaodion, Ifedayo A. Ayanleke, Aanu P. Agunbiade, Emmanuel O. Ogbuagu, Edith O. Airaodion & Uloaku Ogbuagu · International Journal of Research and Reports in Gynaecology · 2020

Background: The use of Jatropha curcas leaves in folklore medicine has gained popularity in recent times due to its medicinal value but without regards to its adverse health effect. Aim: This study aimed at investigating the effect of J. curcas leaves on the fertility of male Wis...

Open access Research Article