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Ugwu Obiora Celestine

0000-0002-6657-4942

Publications (5)

Phytochemical Screening and Ameliorative Potential of Ethyl Acetate Fraction of Polyaltha logifolia Leaves on Croton Oil-induced Hemorrhoid in Albino Wistar Rats

Ugwu Obiora Celestine, Umeakuana Chidinma Doris, Ogbonna Chidera Gloria, Uzoefuna Chima Casmir, Onyima Glory Chinemerem, Adonu Cyril Chekwube, Asogwa Felix Keneolisa, Omeh, Chijioke Romanus, Idokoja Levi Onyebuchi, Offia Ogbonna Raymond, Onah Benjamin Emenike, Pete Princess Oluchukwu & Anosike Chioma Assumpta · International Journal of Biochemistry Research & Review · 2025

Background: Hemorrhoids are a very common anorectal condition defined as the symptomatic enlargement and distal displacement of the normal anal cushions. Aim: The research is aimed at investigating the ameliorative potential of ethyl acetate fraction of Polyaltha logifolia leaves...

Open access Research Article 10.9734/ijbcrr/2025/v34i2959

Assessment of the Potential Mechanisms of Anti-diarrhoeal Activities of Ethanol Extract of Monoon longifolium Leave in Wistar Rat

Ugwu Obiora Celestine, Umeakuana Chidinma Doris, Ogbonna Chidera Gloria, Asadu Chidinma Lilian, Ali Ibeabuchi Jude, Asogwa Felix Keneolisa, Uzoefuna Chima Casmir, Ogbu Chukwudi Collins, Nwokedi Chukwuebuka Kingsley & Anosike Chioma Assumpta · Journal of Advances in Medical and Pharmaceutical Sciences · 2024

Background: Numerous diseases related to diarrhea are the primary cause of morbidity and mortality in underdeveloped countries, accounting for hundreds of thousands of deaths annually. Polyalthia longifolia, the false ashoka, commonly referred to as Monoon longifolium is a tree s...

Open access Research Article 10.9734/jamps/2024/v26i9713

Evaluation of the Anti-inflammatory Effects of Methanol Extract of Rauwofia vomitera Leaves (MERVL) Using In-vivo Based Assays

Ugwu Obiora Celestine, Ukpabi-Ugo Chigozie Jacinta, Asadu Chidinma Lilian, Ali Ibeabuchi Jude, Asogwa Felix Keneolisa, Ugodi Gerald Walter, Obasi Uchenna Emmanuel, Ogbonna Chidera Gloria, Nwokedi Chukwuebuka Kingsley & Anosike Chioma Assumpta · International Journal of Biochemistry Research & Review · 2024

Background of the Study: The response of the body to harmful stimuli, such as tissue damage or a pathogenic infection is known as inflammation.  Rauwofia vomitera is a medicinal plant that is native to large areas of tropical Africa and it belongs to the family of Apocynaceae. It...

Open access Research Article 10.9734/ijbcrr/2024/v33i5877

Anticonvulsant Activity of Methanol Extract of Harungana madagascariensis Leaf on Mice Model of Isoniazid-induced Siezure

Ugwu Obiora Celestine, Ali Ibeabuchi Jude, Felix Keneolisa Asogwa, Okonkwo Raymond Maduabuchi & Nwafor Samuel Nnamdi · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Background: Epilepsy is a neurological illness that affects people of all ages and is characterized by excessive electric activity in the brain. This causes social embarrassment coupled with side effect of orthodox medication; hence, the needs to search for plant with antiepilept...

Open access Research Article 10.9734/jamps/2022/v24i8572

Phytochemical Screening and Antibacterial Evaluation of Anarcardium occidentale Root Collected in Agbani, Eastern Nigeria

Adonu Cyril Chekwube, Ali Ibeabuchi Jude, Omeh Romanus Chijioke, Ujam Treasure Nonye, Okorie Ndidiamaka Hannah, Ugwu Obiora Celestine, Okonkwo Raymond Maduabuchi & Okonkwo Chidubem · Journal of Advances in Medical and Pharmaceutical Sciences · 2023

Background: Different parts of Anacardium occidentale (Cashew) are used in folk medicine to treat dysentery, diarrhea piles, toothache and sore gums. Evaluation of phytoconstituents or novel compounds from the plant is highly needed to authenticate these claims. Aim: The aim of t...

Open access Research Article 10.9734/jamps/2023/v25i3609