Adenylyl cyclase type 2 (ADCY2) is an enzyme linked to membranes that is implicated in the spread of many cancer types and tumors. As such, it may be a target for therapeutic intervention. Using molecular docking, we examined how these compounds bound to ADCY2. Cancer is treated...
Type 2 diabetes mellitus (T2DM) is an intricate and inadequately treatable metabolic disorder that requires modified treatment by identifying genetic variants as potential drug targets. In this study, we performed the system-level genetic analysis of the T2DM-related cDNA dataset...
Open access
Research Article10.9734/ajbgmb/2023/v14i4321
Single nucleotide polymorphisms (SNP) are responsible for genetic mutations. We studied genetic molecular variations and found an association of oral cancer with SNP of Adenylate Cyclase 2 (ADCY2) rs252546 and complement C7 (C7) rs1450656 genes in people of Southern Punjab, Pakis...
Open access
Research Article10.9734/ajbgmb/2021/v9i430225
Background: Over the last few decades, metallic nanoparticles, especially silver nanoparticles (AgNPs), have gained the focus of researchers globally due to their unique properties and a broad range of applications. Aim: This research study focused on the green synthesis of AgNPs...
Open access
Research Article10.9734/ajbgmb/2023/v14i2311
Aims: Proteases are the most deliberate microbial enzyme at mercantile, industrial, health professional, analytic, symptomatic, outgoing interruption and other sectors. Methodology: About 8 isolates were recovered from different soil samples gathered from various fields of Abdul...
Open access
Research Article10.9734/JPRI/2017/37048
Type 2 diabetes mellitus (T2DM) is the most prevailing worldwide health challenge of the 21st century and the 5th leading cause of death worldwide. About 90% of diabetic patients are diagnosed as having T2DM. LPAR1 gene codes LPA protein that is involved in the regulation of many...
Open access
Research Article10.9734/ajbgmb/2022/v11i430279
Genetic variations could be involved in the pathogenesis of diabetes. Type 2 diabetes (T2DM) accounts for 90% of all diabetes cases worldwide, however, the percentage is higher in the South Asian region. In this study, we observed the single nucleotide polymorphism (SNP) in GTF2H...
Open access
Research Article10.9734/ajbgmb/2022/v10i130237