Richard Adedamola Ajike, Oladele Ayobami Afolabi, Ayodeji Folorunsho Ajayi, Olajumoke Deborah Ogunleye, Waidi Adeoye Saka, Olusola Bamidele & Oluwaseun Samuel Hezekiah·International Journal of Biochemistry Research & Review·2024
This study investigated the effects of sequential administration of febuxostat, amlodipine, and vitamin E on oxidative stress and spermatogenesis following testicular ischemia-reperfusion injury (TIRI) in Wistar rats. Ninety male rats (120-150 g) were divided into 9 groups (n=10...
Open access
Research Article10.9734/ijbcrr/2024/v33i6894
Background: Cadmium, a known genotoxic metal, has been shown to worsen colonic damage in both animal models and human studies. Research has indicated that cadmium accumulation in the colon results in mucosal damage, inflammation, disrupted immune responses, and an increased risk...
Oreoluwa Janet Adedeji, Oladele Ayobami Afolabi, Richard Adedamola Ajike, Olubunmi Simeone Oyekunle, Waidi Adeoye Saka, Olajumoke Deborah Ogunleye, Bamidele Oluwole Olusola, Oluwaseun Samuel Hezekiah, Sodiq Opeyemi Hammed & Babatunde Adebola Alabi·Journal of Advances in Biology & Biotechnology·2024
Introduction: Testicular ischemia-reperfusion injury (TIRI) generates reactive oxygen species (ROS) through xanthine oxidase (XO) activity in the ischemic phase and leukocyte infiltration to the site of injury during reperfusion leading to oxidative stress, inflammation, and disr...
Open access
Research Article10.9734/jabb/2024/v27i121800
Cognitive deficit, more common with age, it affects memory and cognitive functions. Intestinal ischemia-reperfusion injury (IIRI) causes systemic inflammation that can damage the brain, particularly the hippocampus. Curcumin, an active ingredient found in turmeric have neuroprote...
Open access
Research Article10.9734/jalsi/2025/v28i1676