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Okolonkwo, Benjamin Nnamdi

Publications (4)

A Biological Trial on the Effect of Vitamin E and C Combination Therapy on Chronic Paraquat Toxicity

Okolonkwo, Benjamin Nnamdi, Jonathan, Nyebuchi, Adjekuko, Ohwonigho Collins & Zebedee, Loveday Udu · Annual Research & Review in Biology · 2022

Paraquat (1,1-dimethyl-4-4-bipiridinium dichloride (PQ) is a non-selective contact herbicide that is a major source of free radicals and generates superoxide anion, and reactive oxygen species (ROS) which causes severe oxidative damage. Vitamin C is a water-soluble vitamin that p...

Open access Research Article 10.9734/arrb/2022/v37i530510

Synergistic Effect of Vitamin E and C Treatment on Paraquat Induced Haemotoxicity in Rattus norvegicus

Okolonkwo, Benjamin Nnamdi, Jonathan, Nyebuchi, Adjekuko, Ohwonigho Collins & Zebedee, Loveday Udu · Advances in Research · 2022

Paraquat is a herbicide, commonly used in the agricultural practices to prevent weed infestation. The Environmental Protection Agency in some countries has placed a restriction on paraquat and there is no identified record of chelating agent or antidote for paraquat. Oxidation of...

Open access Research Article 10.9734/air/2022/v23i330334

Ameliorative Effect of Vitamin E on Paraquat Induced Haematological Disorder in Male Albino Rats

Okolonkwo, Benjamin Nnamdi, Jonathan, Nyebuchi, Adjekuko, Ohwonigho Collins & Zebedee, Loveday Udu · Biotechnology Journal International · 2022

Paraquat is a controversial herbicide that can increase reactive oxygen species levels by undergoing redox cycling and producing reactive oxygen species such superoxide anion. Vitamin E is a fat soluble vitamin that modulates oxidation processes in the body due to its particular...

Open access Research Article 10.9734/bji/2022/v26i230168

Study on the Therapeutic Benefits of Vitamin E after Paraquat Toxicity

Okolonkwo, Benjamin Nnamdi, Jonathan, Nyebuchi, Adjekuko, Ohwonigho Collins & Mieiwari, Ibifubara Jumbo · Journal of Scientific Research and Reports · 2022

The Paraquat (1, 1-dimethyl-4,4-bipyridlium dichloride) is a non-selective nitrogen herbicide that is used for broadleaf control of weed. It has been shown that paraquat is toxic to human and animal. Vitamin E (α-tocopherol) is a lipid soluble antioxidant found in all cellular me...

Open access Research Article 10.9734/jsrr/2022/v28i530520