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O. I. N. Onyekachi

Publications (6)

Hepatocellular Injury Ameliorated by a Common African Food, Parkia biglobosa

O. I. N. Onyekachi, S. F. Orji, C. N. Ugwu, C. Igwenyi, C. L. Uche, I. O. Abali, M. U. Nwobodo, C. E. Iwuoha, N. M. Chika-Igwenyi, C. A. Onyeaghala, F. U. Agu & A. I. Airaodion · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2022

Background: Parkia biglobosa seed has been reported to possess hepatoperotective potential. Therefore, this study sought to investigate its ability in ameliorating KBrO3-induced hepatotoxicity. Methodology: P. biglobosa was extracted with soxhlet extractor with 95% ethanol as the...

Open access Research Article 10.9734/ajrimps/2022/v11i4199

Prophylactic Potential of Corchorus olitorius Leaves against Experimentally-induced Dyslipidaemia

C. N. Ugwu, I. O. Abali, F. U. Agu, K. J. Aguh, O. I. N. Onyekachi, M. U. Nwobodo, N. M. Chika-Igwenyi, C. A. Onyeaghala, C. L. Uche, S. F. Orji, C. Igwenyi & A. I. Airaodion · Asian Journal of Cardiology Research · 2022

Background: Our literature searches revealed that no study has examined the ameliorative impact of Corchorus olitorius leaves on dyslipidaemia caused by potassium bromate (KBrO3). Therefore, the purpose of this study was to determine whether C. olitorius leaves could prevent KBrO...

Open access Research Article

Attenuation of Potassium Bromate-induced Infertility by African Locust Bean (Parkia biglobosa) Seed

E. O. Ezirim, C. A. Onyeaghala, S. F. Orji, C. N. Ugwu, C. Igwenyi, C. L. Uche, I. O. Abali, O. I. N. Onyekachi, M. U. Nwobodo, F. U. Agu, C. E. Iwuoha, N. M. Chika-Igwenyi & A. I. Airaodion · Asian Journal of Medicine and Health · 2022

Background: Parkia biglobosa seed has been reported to enhance sperm quality. Thus, this study sought to assess its ability in attenuating KBrO3-induced sperm abnormalities. Methodology: P. biglobosa was extracted with soxhlet extractor with 95% ethanol as the solvent. Twenty-fou...

Open access Research Article 10.9734/ajmah/2022/v20i1130533

Chemotherapeutic Propensity of Africa Locust Bean (Parkia biglobosa) Seed on Lipid Profile against Potassium Bromate-induced Cardiotoxicity

C. N. Ugwu, C. E. Iwuoha, N. M. Chika-Igwenyi, C. A. Onyeaghala, S. F. Orji, C. Igwenyi, C. L. Uche, O. I. N. Onyekachi, M. U. Nwobodo, I. O. Abali & A. I. Airaodion · Journal of Applied Life Sciences International · 2022

Background: Cardiovascular disease cases are on the increase despite many standard medical practices. Some disorders have been successfully treated by medicinal plants. Aim: The current study was designed to assess the chemotherapeutic propensity of Parkia biglobosa against potas...

Open access Research Article 10.9734/jalsi/2022/v25i530306

Perturbation of Sex Hormones by Potassium Bromate and Preventive Effect of African Locust Bean (Parkia biglobosa) Seed

C. E. Iwuoha, E. O. Ezirim, C. A. Onyeaghala, S. F. Orji, C. N. Ugwu, C. Igwenyi, C. L. Uche, I. O. Abali, O. I. N. Onyekachi, M. U. Nwobodo, F. U. Agu, N. M. Chika-Igwenyi & A. I. Airaodion · Asian Journal of Research in Biochemistry · 2022

Background: African locust bean is used for medicinal purposes in African countries for the treatment of various diseases. However, no study has reported its ameliorative effect on sex hormones perturbations. This study, therefore, sought to investigate its preventive effect agai...

Open access Research Article 10.9734/ajrb/2022/v11i1203

Nephro-protective Efficacy of African Locust Bean Seed against Potassium Bromate-induced Renal Damage

I. O. Abali, N. M. Chika-Igwenyi, F. U. Agu, C. A. Onyeaghala, S. F. Orji, C. N. Ugwu, C. Igwenyi, C. L. Uche, O. I. N. Onyekachi, M. U. Nwobodo, C. E. Iwuoha & A. I. Airaodion · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

Background: Potassium bromate (KBrO3) has been utilized extensively to sterilize water, dye hair, oxidize food, add to bread dough as a maturing agent, and condition wheat dough, thereby entering into human body. It has been claimed to cause a number of toxicities including nephr...

Open access Research Article 10.9734/ajbgmb/2022/v12i3264