Background: The annual and aromatic plant known as Trachyspermum ammi L. Sprague belongs to the family Apiaceae. The in vivo antidiabetic efficacy of crude extract extracted from Trachyspermum ammi leaves was assessed in the current study. Study Design: This study engaged in vivo...
Open access
Research Article10.9734/ijbcrr/2023/v32i10844
Aim: An essential medicinal plant, Echhornia crassipes is a member of the Pontederiaceae family and is used to treat a wide range of disorders. Using various animal models, this study sought to investigate the anti-inflammatory and wound-healing benefits of an ethanolic extract o...
Open access
Research Article10.9734/ajriz/2023/v6i4132
AIM: The purpose of this study was to explore the possible mechanisms through which Trachyspermum ammi may be beneficial in managing diabetes by in vitro methods and to predict the potential bioactive constituent/s responsible for its anti-diabetic activity through in silico dock...
Open access
Research Article10.9734/ajrb/2023/v13i4268
The reaction characterized by inflammation in the brain or the spinal column is known medically as "neuroinflammation." The central nervous system is impacted by neurodegeneration, which is epitomized by the loss of neural functioning and structure. Neurodegeneration occurs as a...
Hyperlipidemia describes a group of genetic along with medical conditions which raise cholesterol levels throughout the bloodstream. Many individuals suffer from this illness. It puts the patient at risk for major problems such heart disease, brain strokes, hepatic malfunction, a...
M. Ganga Raju, R. Manisha, NVL Suvarchala Reddy V. & P. Samson Simharayullu·Asian Journal of Biology·2022
The present research is focused on screening In vivo anti-inflammatory activity using carrageen and formalin induced paw edema model in rodents and In silico approaches like docking studies (mcule), Ramchandran plot (procheck) and PASS. The extract significantly inhibited inflamm...
Open access
Research Article10.9734/ajob/2022/v15i330242
The majority of epileptic patients takes numerous anticonvulsant medications and is still not treated successfully. These medications' produce chronic side effects and drug interactions, which restrict their use, constitute their major drawback. On the other hand, the fact that n...
Open access
Research Article10.9734/indj/2022/v17i330206
Aims: The present research is focused on screening in vivo and insilico anti- amnesic activity of the ethanolic extract of seeds of Chenopodium quinoa. To establish the exact the mechanism of action, the phytochemical constituents of the extract were subjected to in silico studie...
Open access
Research Article10.9734/jalsi/2022/v25i430300
Flax also known as common flax or linseed, is a flowering plant, Linum usitatissimum, in the family Linaceae. The current study used haloperidol-induced catalepsy and reserpine antagonism to investigate in vivo anti- Parkinson's activity and in silico approaches like docking stud...
Open access
Research Article10.9734/jocamr/2022/v17i330333
Rutin was evaluated for its antihypertensive effect by In vitro ACE inhibitory activity using Captopril as standard. For molecular docking the proteins namely PDB ID: 1UZE, 1O86, 2XY9 and 3L3N are selected and modelled. The abilities of the 3D model were assessed via the PROCHECK...
Open access
Research Article10.9734/jocamr/2022/v17i230326
New drug delivery technologies are transforming drug discovery and development, as well as establishing research and development-focused pharmaceutical firms that are accelerating global progress. The bioactive rutin molecule is used in a wide range of food and medicinal goods. I...
Open access
Research Article10.9734/ajrimps/2022/v11i130180
Aims: The present research is focused on screening in vivo anti-ulcer activity using pylorus ligation and ethanol induced ulcer model. Study Design: Fourty eight rats, randomly divided into eight groups, were used in this study. Bark of Alstonia scholaris were air-dried, ground...
Open access
Research Article10.9734/ajrimps/2022/v11i130179
Aim: The present study explored the pharmacological and insilico studies of ethanolic seed extract of Chenopodium quinoa. Materials and Methods: The screening of in vivo anti- amnesic activity of the ethanolic seed extract of Chenopodium quinoa was carried out using Actophotomete...
Open access
Research Article10.9734/jamps/2021/v23i1130270
Depression is a complex mental disorder that not only affects mood but also poses a significant risk factor for the development of Alzheimer’s disease. Key findings unravel a bilateral relationship where depression not only emerges as a precursor but also as a consequence of Alzh...
Open access
Research Article10.9734/jpri/2024/v36i67518
Diabetes is a frequent metabolic complaint associated with increasing blood sugar levels, it also has a connection to long- term vascular problems that can damage blood vessels, urinary tract, sight, and neurons. By adding amino acid breakdown and ultimately accumulating complex...
Open access
Research Article10.9734/ajrb/2023/v13i3262
Around the world, 50 million people suffer with epilepsy; it significantly burdens society in terms of finances, society, and health. Our comprehension of the pathophysiological processes causing the illness and the factors affecting its prognosis has significantly advanced durin...
Open access
Research Article10.9734/irjpac/2023/v24i5824
The goal of the current study was to identify potential bioactive components that may be responsible for Rhynchosia beddomei's antidiabetic activity through in silico docking study and to investigate potential mechanisms by which Rhynchosia beddomei may be helpful in managing dia...
Open access
Research Article10.9734/jpri/2023/v35i197395
In animal models for screening for anticonvulsant activity, it has been scientifically established that medicinal herbs used in traditional medicine for the treatment of epilepsy possess promising anticonvulsant properties and can be a source of newer anticonvulsants. This study'...
Open access
Research Article10.9734/indj/2022/v18i130212
The swimming endurance test, anoxic tolerance test, and basal activity by actophotometer were used to assess the antistress activity of a seven-day therapy (200 and 400 mg/kg, p.o.) of the ethanolic extract of Coriandrum sativum (EECS) aerial parts. A method for measuring the in...
Open access
Research Article10.9734/aprj/2022/v9i430212
Aim: To evaluate anti-hyperlipidemic activity of the whole plant of Gossypium herbaceum extract in Wistar Albino Rats. Methods: The whole plant of Gossypium herbaceum were collected and extracted with methanol by soxhlation. It was tested in Triton and Propylthiouracil (PTU) indu...
Open access
Research Article10.9734/ajrimps/2022/v11i330193