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John A. Ekenjoku

Publications (11)

Oral Administration of Ethanolic Leaf Extract of Vernonia amygdalina May Impact Negatively on Fertility in Male Wistar Rats

John A. Ekenjoku, Augustine I. Airaodion, Victor N. Okoroukwu, Emmanuel O. Ogbuagu & Uloaku Ogbuagu · Asian Journal of Medical Principles and Clinical Practice · 2019

Background: The use of Vernonia amygdalina leaves as vegetables and in folklore medicine for therapeutic activities is on the increase globally. Aim: This study, therefore, sought to investigate the antifertility effect of V. amygdalina leaves in male Wistar rats. Methods: Fresh...

Open access Research Article

Antibacterial Potential of Ethanolic and Aqueous Extracts of Carica papaya Leaves

Augustine I. Airaodion, John A. Ekenjoku, Ime U. Akaninyene & Anthony U. Megwas · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2020

Background: The search for newer sources of antibiotics is a global challenge pre-occupying research institutions, pharmaceutical companies and academia, since many infectious agents are becoming resistant to synthetic drugs. Aim: This present study sought to investigate the anti...

Open access Research Article 10.9734/ajbgmb/2020/v3i330088

Consumption of Coconut (Cocos nucifera L.) Water Improved Fertility Parameters in Male Wistar Rats

A. I. Airaodion, John A. Ekenjoku, Kenneth O. Ngwogu & Ada C. Ngwogu · Asian Journal of Pregnancy and Childbirth · 2020

Background: The need for fertility stimulation in men and women cannot be overemphasized especially when a marriage is childless in some communities in Nigeria. While chemical methods for fertility stimulation may have some side effects and are not readily available, remedy from...

Open access Research Article 10.9734/ajpcb/2019/v2i120

Carica papaya Leaves Might Cause Miscarriage

Augustine I. Airaodion, John A. Ekenjoku, Emmanuel O. Ogbuagu, Victor N. Okoroukwu & Uloaku Ogbuagu · Asian Research Journal of Gynaecology and Obstetrics · 2019

Background: The use of Carica papaya leaves in folklore medicine for its antimalarial and antidiabetic activities is on the increase globally. Aim: This was undergone to investigate if C. papaya leaves have the propensity to induce miscarriage during pregnancy. Methods: Fresh and...

Open access Research Article

Hepatoprotective Potency of Ethanolic Extract of Garcinia kola (Heckel) Seed against Acute Ethanol-induced Oxidative Stress in Wistar Rats

Augustine I. Airaodion, Ada C. Ngwogu, John A. Ekenjoku & Kenneth O. Ngwogu · International Research Journal of Gastroenterology and Hepatology · 2020

Aim: Hepatoprotective potency of ethanolic extract of Garcinia kola (Heckel) seed against acute ethanol-induced oxidative stress in Wistar rats. Materials and Methods: G. kola seeds were purchased from a local market in Ibadan, Nigeria. The seeds were chopped to smaller pieces af...

Open access Research Article

Bigi Soft Drinks might Induce Hyperglycemia and Hyperlipidemia in Wistar Rats

Augustine I. Airaodion, Emmanuel O. Ogbuagu, John A. Ekenjoku, Victor N. Okoroukwu & Uloaku Ogbuagu · International Journal of Research and Reports in Hematology · 2019

Background: Bigi soft drinks are carbonated drinks produced by Rite Foods Limited. The company is an indigenous company in Nigeria. Before 2016, Coca-cola bottling company and 7up bottling company products were the dominant soft drinks in Nigeria. Rite Foods Limited introduced ca...

Open access Research Article

Effect of Common Household Insecticides Used in Nigeria on Rat Male Reproductive Hormones

Augustine I. Airaodion, Ada C. Ngwogu, Anthony U. Megwas, John A. Ekenjoku & Kenneth O. Ngwogu · International Journal of Research and Reports in Gynaecology · 2020

Background: The use of household insecticides for the eradication of insects especially mosquitoes in Nigeria is increasing. These insecticides are used without consideration of their adverse effect on human health. Aim: This study was aimed at accessing the effect of common hous...

Open access Research Article

Pharmacotherapeutic Activity of Allium sativum (Garlic) Bulb against Gram-positive and Gram-negative Bacteria

A. I. Airaodion, Ada C. Ngwogu, Kenneth O. Ngwogu, John A. Ekenjoku & Anthony U. Megwas · Asian Journal of Research in Infectious Diseases · 2020

Background: Emergence of methicillin drug resistance is evident and has become a global challenge. Seeking for alternative antibiotics that are new, natural, plant based, cost effective and less toxic is the recent task for global health. Aim: This study is aimed at assessing the...

Open access Research Article 10.9734/ajrid/2020/v3i330128

Common Household Insecticides Used in Nigeria Induced Oxidative Stress in Wistar Rats

Augustine I. Airaodion, Kenneth O. Ngwogu, Ada C. Ngwogu, Anthony U. Megwas, John A. Ekenjoku & Olaide O. Awosanya · Asian Journal of Immunology · 2020

Background: The use of household insecticides for the eradication of insects especially mosquitoes in Nigeria is increasing. These insecticides are used without consideration of their adverse effect on human health. Aim: This study is therefore sought to investigate the effect of...

Open access Research Article

Nephrotoxicity of Monosodium Glutamate (MSG) in Wistar Rats

Augustine I. Airaodion, Kenneth O. Ngwogu, Ada C. Ngwogu, Anthony U. Megwas & John A. Ekenjoku · International Journal of Advances in Nephrology Research · 2020

Background: Nowadays, monosodium glutamate (MSG) is frequently used as a flavour enhancer, the fact of which makes it one of the most applied food additives in modern nutrition all over the world. But accurate information on the daily intake of specific food additives by individu...

Open access Research Article

Effect of Monosodium Glutamate on Body Weight and Alanine Aminotransferase Activity in Wistar Rats

Emmanuel O. Ogbuagu, Augustine I. Airaodion, Victor N. Okoroukwu, Uloaku Ogbuagu & John A. Ekenjoku · International Research Journal of Gastroenterology and Hepatology · 2019

Background: In recent days, the use of seasonings to enhance the flavor of food has been increased. A variety of seasonings are produced now days and the constituents of these flavor-enhancers are unknown to ignorant consumers. The consumers were preferred to eat food with good t...

Open access Research Article