Objective: The anti-diarrhoea activity of the aqueous extract of the stem bark of C. aurantifolia was investigated in this study. Materials and Methods: Acute toxicity evaluation of the aqueous extract of C. aurantifolia stem bark was carried out using rats according to Lorke’s m...
Open access
Research Article10.9734/AJRIMPS/2018/45419
Aims: This study comparatively evaluated the radical scavenging activity of the methanolic extracts of five indigenous plants, namely- Zingiber officinale (Zingiberaceae), Nauclea latifolia (Rubiaceae), Phyllantus spp (Euphorbiaceae), Khaya senegalensis (Meliaceae) and Camellia s...
Open access
Research Article10.9734/IJBCRR/2016/23974
Aim: To investigate the laxative potentials of aqueous leaf extract of Sida acuta in loperamide-induced constipation in Wistar rats. Methods: Constipation was induced by oral administration of loperamide (3 mg/kg b.wt.). The constipated rats were orally treated daily either with...
Open access
Research Article10.9734/ajrimps/2019/v6i130093
Aim: This study evaluated the nephroprotective effect of methanol extract of Hymenocardia acida leaves in rat model of gentamicin induced renal damage. Materials and Methods: Twenty- four (24) Wistar albino rats of either sex weighing 150- 200g were divided into 4 groups of 6 ani...
Open access
Research Article10.9734/ajrb/2018/v3i229818
Nweje- Anyalowu Paul Chukwuemeka, Anyalogbu Ernest Anayochukwu Aniemeka, Idakwoji Precious Adejoh, Agatemor Uzuazokaro Mark-Maria & Uroko Robert Ikechukwu·International Blood Research & Reviews·2019
Objective: This study was undertaken to validate the haematinic potentials of the aqueous leaf extracts of Ficus exasperata (FEAE) and Telfeira occidentalis (TOAE) administered separately and to establish a possible synergistic interaction when administered concurrently to chlora...
Open access
Research Article10.9734/ibrr/2019/v9i330100
Agatemor Uzuazokaro Mark- Maria, Ozioko Eucharia Ngozi, Momoh Theophilus Boniface, Idakwoji Precious Adejoh & Nweje- Anyalowu Paul Chukwuemeka·Asian Journal of Research in Biochemistry·2019
In this study the antidiabetic effect of a polyherbal formulation- ZPC was investigated in Wistar rats. Diabetes was induced by intraperitoneal injection of streptozotocin at a dose of 50 mg/kg. Rats having Fasting Blood Sugar (FBS) level above 250 mg/dl after 72 hrs were conside...
Open access
Research Article10.9734/ajrb/2019/v4i330071
Iserhienrhien Lucky Osafanme, Sheneni Victor Duniya, Nweje-Anyalowu Paul Chukwuemeka, Oguche Mercy & Idakwoji Precious Adejoh·Asian Journal of Research in Biochemistry·2019
Aim: The haematinic activity of the aqueous extract of Lophira lanceolata leaves was investigated using rat model of phenylhydrazine-induced anaemia. Methods and Results: Red Blood Cell (RBC) count, Haemoglobin (Hb) concentration and Packed Cell Volume (PCV) were analysed as indi...
Open access
Research Article10.9734/ajrb/2019/v4i130057