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İbrahim Bulduk

Publications (8)

Spectrophotometric and High Performance Liquid Chromatographic Determination of Carbamazepine in Tablets Dosage Form

İbrahim Bulduk & Serdar Gungor · Journal of Pharmaceutical Research International · 2021

Today, millions of people suffer from epilepsy, one of the most common chronic neurological diseases worldwide. Carbamazepine is a first-line drug used in the treatment of epilepsy. High performance liquid chromatographic and spectrophotometric methods have been developed for the...

Open access Research Article 10.9734/jpri/2021/v33i47A33068

Evaluation of Galantamine, Phenolics, Flavonoids and Antioxidant Content of Galanthus Species in Turkey

İbrahim Bulduk & Yasemin Sunucu Karafakıoğlu · International Journal of Biochemistry Research & Review · 2019

Aims: The aim of the present study was to determine the total phenolic and flavonoid content and antioxidant activities in Galanthus species (Gaalanthus woronowii, Galanthus nivalis, and Galanthus elwesii) indigenous to Turkey. Study Design: The plant materials used in the study,...

Open access Research Article 10.9734/ijbcrr/2019/v25i130068

Analytical Methods for the Quantification of Ribavirin in Pharmaceutical Preparations, A Comparative Study

Serdar Gungor & İbrahim Bulduk · Journal of Pharmaceutical Research International · 2022

Ribavirin is a broad-spectrum antiviral drug and is used to treat diseases caused by many viral infections. In this study, high-pressure liquid chromatographic and UV-Vis spectrophotometric methods were developed, validated and statistically compared to determine the amount of ri...

Open access Research Article 10.9734/jpri/2022/v34i13A35569

Chromatographic Method for Quantification of Tenofovir in Pharmaceutical Formulations: Comparison with Spectrophotometric Method

Erten Akbel & İbrahim Bulduk · Journal of Pharmaceutical Research International · 2021

Aims: An efficient therapeutic drug or antiviral agent to treat Covid-19 is still not available. But, previously licensed pharmaceuticals to treat other virus infections are usedon an off-label basis either alone or in combination. Tenofovir emerged as a promising treatment for C...

Open access Research Article 10.9734/jpri/2021/v33i49A33330

An İn vitro Study on Anticancer Activity of Noscapine

Funda Karabağ Çoban, İbrahim Bulduk, İzzet İslam & Hande Aytuğ · Journal of Pharmaceutical Research International · 2021

Aims: Breast cancer is the most common type of cancer among women and ranks second among the causes of female death in the world. In order to find a solution to breast cancer, different studies are being conducted for the treatment and the effects of different drugs and substance...

Open access Research Article 10.9734/jpri/2021/v33i1131246

Total Phenolics, Flavonoids Contents, Antioxidant Activity and DNA Protective Effect of Lenten Rose (Helleborus orientalis)

Meral Öztürk, İbrahim Bulduk, Safiye Elif Korcan, Recep Liman, Funda Karabağ Çoban, Mustafa Kargıoğlu & Muhsin Konuk · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2019

The aims of the present study were to evaluate the antioxidant activity and DNA Protective effect of Helleborus orientalis (HO) leaf extract against oxidative damage, and to determine the total phenolic and flavonoid contents of the plant species studied. Methods: The total pheno...

Open access Research Article 10.9734/ajbgmb/2018/v1i430047

Synthesis of Morphine Loaded Hydroxyapatite Nanoparticles (HAPs) and Determination of Genotoxic Effect for Using Pain Management

Hava Kölemek, İbrahim Bulduk, Yavuz Ergün, Muhsin Konuk, S. Elif Korcan, Recep Liman & Funda Karabağ Çoban · Journal of Pharmaceutical Research International · 2019

Morphine is used as a standard analgesic for intensive pain relief. It relieves acute and chronic pain by acting directly on the central nervous system and to treat myocardial infarction and shortness of breath. However, the use of morphine for the alleviation of chronic pain is...

Open access Research Article 10.9734/jpri/2018/v25i630116

Development and Validation of UPLC-MS / MS Method for Obtaining Favipiravir Tablet Dosage form and Evaluation of its Behavior Under forced Conditions

Süleyman Gökçe, Ayşen Höl & İbrahim Bulduk · Journal of Pharmaceutical Research International · 2021

Aims: Favipiravir (FVP) is a drug developed against RNA viruses. It is a drug that is used actively in the treatment of coronavirus. In vitro and in vivo investigations have shown that it inhibits the virus. In this study, a recovery study of tablet formulations was carried out b...

Open access Research Article 10.9734/jpri/2021/v33i56A33895