H. M. Vagdevi

Synthesis of Novel 3-methyl-1-(5-methyl-1,3-benzoxazol-2-yl)-1H-pyrazol-5-amine Derivatives and In-vitro Evaluation of their Antitumor and Antibacterial Activities

J. Paveendra & H. M. Vagdevi · Journal of Pharmaceutical Research International · 2023

Benzoxazole is one of the biologically important heterocyclic compounds, which shows remarkable pharmacological activities. In this work, 3-methyl-1-(5-methyl-1,3-benzoxazol-2-yl)-1H-pyrazol-5-amine derivatives have been synthesized by using mild protocol under solvent free condi...

Open access Research Article 10.9734/jpri/2023/v35i137367

Solvent free Synthesis of 2-[(5-methyl-1,3-benzoxazol-2-yl)sulfanyl] Acetohydrazide Derivatives as Novel Antimicrobial and Antitumor Agents

J. Paveendra, H. M. Vagdevi, Dyamanna Thippeswamy & Yanjerappa Arthobha Nayaka · Journal of Pharmaceutical Research International · 2023

In pursuit of designing novel chemical entities with antitumor and antimicrobial activities, 2-[(5-methyl-1,3-benzoxazol-2-yl)sulfanyl]acetohydrazidederivatives have been synthesized as a scaffold of a series of amine derivatives, these analogs were on reductive amination with so...

Open access Research Article 10.9734/jpri/2023/v35i137368

Design, Synthesis, Molecular Docking and Biological Evaluation of Novel 2-[(2-{[5-(Pyridin-4-yl)-1, 3, 4-Oxadiazol-2-yl]Sulfanyl}Ethyl)Sulfanyl]-1,3-Benzoxazole

Anees Fathima, H. M. Vagdevi, N. D. Jayanna, R. Mohammed Shafeeulla & . Subbaraju · Journal of Pharmaceutical Research International · 2021

In the present communication, a simple and facile method was adopted to synthesize  a series of novel 2-[(2-{[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]sulfanyl}ethyl)sulfanyl]-1,3-benzoxazole by fusing 5-(pyridin-4-yl)-1,3,4-oxadiazole-2-thiol with substituted 2-[(2-bromoethyl)sulfa...

Open access Research Article 10.9734/jpri/2021/v33i44A32640