Gbenga Opeyemi Owolabi, Victoria Oyamhendan Obasanya, Toluwalase Oyenike Oyewale, Jesuferanmi Ayomiposi Owopetu & Helen Omowumi Afeni·Archives of Current Research International·2025
Psychological stress which is on the increase daily has emerged as a major contributor to the onset and progression of kidney disorders by promoting established risk factors such as hypertension and diabetes. Furthermore, stress is often associated with sleep loss and both factor...
Open access
Research Article10.9734/acri/2025/v25i91534
Gbenga Opeyemi Owolabi, Onaopepo Abdulwakeel Lawal, Helen Omowumi Afeni, Faith Yetunde Oluponmile & Toheeb Ademola Jimoh·Archives of Current Research International·2025
Co-exposure to psychological and physiological stressors, such as acute restraint stress and REM sleep deprivation, may have harmful effects on hepatic integrity that are synergistic. This study investigated the effects of combined acute restraint stress and REM sleep deprivation...
Open access
Research Article10.9734/acri/2025/v25i91526
Gbenga Opeyemi Owolabi, Folashade Helen Otitoju, Muaphat Olayinka Bamidele & Ayomikun Samuel Omoniru·Advances in Research·2025
Heavy metals, such as cadmium, are toxic, and the kidney is one of their major target organs. Restraint stress, on the other hand, is a model of chronic stress used to mimic human psychological stress. This study aimed to evaluate the effects of restraint stress and cadmium admin...
Open access
Research Article10.9734/air/2025/v26i11259
Psychological stress which is becoming an epidemic due to continental economic meltdown, wars, climate change, disasters has reached a point of global health concern and can be mimicked in rats by restraint stress model. Cadmium chloride is a heavy metal salt whose exposure can b...
Open access
Research Article10.9734/ajob/2024/v20i12463
Cadmium is a toxic heavy metal which promotes oxidative stress in various organs including the brain. Restraint stress is a model of stress which involves physical constraint to induce homeostatic imbalance. This study aimed to evaluate the interaction of restraint stress and cad...
Open access
Research Article10.9734/ajarr/2024/v18i12828
Cadmium (Cd) is known to have some adverse effects on different biochemical and physiological functions causing neurotoxicity leading to neurodegeneration and increasing the risk factor for neurodegenerative disorders. Restraint stress is also associated with changes in behaviora...
Open access
Research Article10.9734/ajrimps/2024/v13i4279
Cadmium (Cd) and prolonged exposure to stress are associated with adverse health outcomes. Various studies have shown the impacts of stress and metal exposures on liver function. Cd is a non-redox metal, one of the important mechanisms underlying its toxicity is oxidative stress...
Open access
Research Article10.9734/ajmah/2024/v22i121131
Lead is a toxic metal and an environmental pollutant that has been associated with an increased incidence of cardiovascular diseases while restraint stress is a psychological stress model that can also potentially induce deleterious effects on cardiac functions. The aim of this s...
Open access
Research Article10.9734/ajarr/2024/v18i12806
Gbenga Opeyemi Owolabi, Adedoyin Esther Adiamo, Onaopepo Abdulwakeel Lawal, David Ibukunoluwa Okanlawon & Omorolade Oluwatobi Osinloye·Asian Journal of Biology·2024
Cadmium is a heavy metal that has been shown to induce metabolic changes while restraint stress is a model of psychological stress used to induce behavioural and physiological changes. This study investigated the combined effect of cadmium chloride administration and restraint st...
Open access
Research Article10.9734/ajob/2024/v20i12458
The kidney is sensitive to heavy metals because of its intensive metabolic activity and multiple functions namely those of excretion and pollutants concentration. The study aimed to evaluate the gender-specific variation in lead-induced nephrotoxicity in Wistar rats. 10 male and...
Open access
Research Article10.9734/ajrimps/2024/v13i4276
Background: Cadmium, a known genotoxic metal, has been shown to worsen colonic damage in both animal models and human studies. Research has indicated that cadmium accumulation in the colon results in mucosal damage, inflammation, disrupted immune responses, and an increased risk...